Mefv - MEFV innate immunity regulator, pyrin Gene

Also Known as pyrin

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 58923

Summary

Predicted to enable actin binding activity; identical protein binding activity; and ubiquitin protein Ligase activity. Involved in response to lipopolysaccharide and response to silicon dioxide. Predicted to be located in nucleus. Predicted to be part of microtubule associated complex. Predicted to be active in cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; Sweet syndrome; asthma; familial Mediterranean fever; and hematologic Cancer (multiple). Orthologous to human MEFV (MEFV innate immuity regulator, pyrin). [provided by Alliance of Genome Resources, Apr 2022]

Mefv Products (1)

mRNA Protein Name
NM_031634.2 NP_113822.2 pyrin

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
16574623 RGD
involved in response to silicon dioxide IEP
IEP: Inferred from expression pattern
16574623 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pyrin

  • MEFV innate immuity regulator, pyrin

  • MEFV, pyrin innate immunity regulator

  • Mediterranean fever

  • marenostrin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08313 MEFV Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20773 Mefv Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27287 Mefv Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mefv NCBI NCBI:4210