Lypd3 - Ly6/Plaur domain containing 3 Gene

Also Known as C4.4a

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 60378

Summary

Enables laminin binding activity. Acts upstream of or within cell-matrix adhesion. Located in membrane. Is integral component of membrane. Orthologous to human LYPD3 (LY6/PLAUR domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]

Lypd3 Products (1)

mRNA Protein Name
NM_021759.1 NP_068527.1 ly6/PLAUR domain-containing protein 3 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables laminin binding IDA
IDA: Inferred from direct assay
15729693 RGD
Biological Process GO Annotation Evidence References Source
acts upstream of or within cell-matrix adhesion IDA
IDA: Inferred from direct assay
15729693 RGD
Cellular Component GO Annotation Evidence References Source
located in membrane IDA
IDA: Inferred from direct assay
15729693 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ly6/PLAUR domain-containing protein 3

  • GPI-anchored metastasis-associated protein C4.4A

  • GPI-anchored metastasis-associated protein homolog

  • metastasis-associated GPI-anchored protein

  • metastasis-associated molecule

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99719 Lupartumab Amadotin 99.61% Phase 1
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99718 Lupartumab 99.52% Phase 1

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-147281 BAY 1135626 99.19% Unkown
HY-RS07917 LYPD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17704 Lypd3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24168 Lypd3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992360 GT-002 Modulator / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lypd3 NCBI NCBI:27076