STX7 - Stx7 syntaxin 7 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 60466

Summary

Enables SNAP receptor activity and SNARE binding activity. Involved in endosome to lysosome transport and vesicle fusion. Located in late endosome membrane and lysosomal membrane. Part of SNARE complex. Is integral component of synaptic vesicle membrane. Orthologous to human STX7 (syntaxin 7). [provided by Alliance of Genome Resources, Apr 2022]

STX7 Products (1)

mRNA Protein Name
NM_021869.2 NP_068641.2 syntaxin-7

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables SNAP receptor activity IDA
IDA: Inferred from direct assay
15133481 RGD
enables SNARE binding IPI
IPI: Inferred from physical interaction
15133481 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
14668490 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
11786915 RGD
Biological Process GO Annotation Evidence References Source
involved in endosome to lysosome transport IDA
IDA: Inferred from direct assay
15133481 RGD
involved in vesicle fusion IDA
IDA: Inferred from direct assay
15133481 RGD
involved in vesicle-mediated transport IDA
IDA: Inferred from direct assay
15133481 RGD
Cellular Component GO Annotation Evidence References Source
part of SNARE complex IDA
IDA: Inferred from direct assay
11786915 RGD
located in endosome IDA
IDA: Inferred from direct assay
11786915 RGD
located in late endosome membrane IDA
IDA: Inferred from direct assay
15133481 RGD
located in lysosomal membrane IDA
IDA: Inferred from direct assay
15133481 RGD
is active in synaptic vesicle membrane EXP
EXP: Inferred from Experiment
17110340 RGD
is active in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
17110340 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

syntaxin-7

  • syntaxin-7-like

Recombinant STX7 Proteins

Cat. No. Product Name Accession Purity
HY-P73620 Syntaxin-7 Protein, Rat (HEK293, His) O70257/NP_068641.2 (S2-L238) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-183079 ENDO12 Inhibitor / Unkown
HY-RS13987 STX7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19164 Stx7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25653 Stx7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens STX7 NCBI NCBI:8417