Slc29a1 - solute carrier family 29 (nucleoside transporters), member 1 Gene

Also Known as ENT1; 1200014D21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 63959

Summary

Enables AMP transmembrane transporter activity; neurotransmitter transmembrane transporter activity; and purine nucleoside transmembrane transporter activity. Involved in adenosine transport; neurotransmitter uptake; and purine nucleoside transmembrane transport. Acts upstream of or within nucleoside transport. Located in plasma membrane. Is expressed in several structures, including central nervous system; hemolymphoid system; hindlimb phalanx; liver; and skeletal musculature. Used to study alcohol dependence and diffuse idiopathic skeletal hyperostosis. Orthologous to human SLC29A1 (solute carrier family 29 member 1 (Augustine blood group)). [provided by Alliance of Genome Resources, Apr 2022]

Slc29a1 Products (18)

mRNA Protein Name
NM_001199113.2 NP_001186042.1 equilibrative nucleoside transporter 1 isoform 1
NM_001199114.2 NP_001186043.1 equilibrative nucleoside transporter 1 isoform 1
NM_001199115.2 NP_001186044.1 equilibrative nucleoside transporter 1 isoform 2
NM_001199116.2 NP_001186045.1 equilibrative nucleoside transporter 1 isoform 2
NM_001357771.2 NP_001344700.1 equilibrative nucleoside transporter 1 isoform 2
NM_001376987.1 NP_001363916.1 equilibrative nucleoside transporter 1 isoform 1
NM_001376988.1 NP_001363917.1 equilibrative nucleoside transporter 1 isoform 1
NM_001376989.1 NP_001363918.1 equilibrative nucleoside transporter 1 isoform 1
NM_001376990.1 NP_001363919.1 equilibrative nucleoside transporter 1 isoform 1
NM_001376991.1 NP_001363920.1 equilibrative nucleoside transporter 1 isoform 2
NM_001376992.1 NP_001363921.1 equilibrative nucleoside transporter 1 isoform 2
NM_001376993.1 NP_001363922.1 equilibrative nucleoside transporter 1 isoform 2
NM_001376994.1 NP_001363923.1 equilibrative nucleoside transporter 1 isoform 2
NM_001376995.1 NP_001363924.1 equilibrative nucleoside transporter 1 isoform 2
NM_001376996.1 NP_001363925.1 equilibrative nucleoside transporter 1 isoform 2
NM_001376997.1 NP_001363926.1 equilibrative nucleoside transporter 1 isoform 3
NM_001376998.1 NP_001363927.1 equilibrative nucleoside transporter 1 isoform 3
NM_022880.4 NP_075018.1 equilibrative nucleoside transporter 1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables neurotransmitter transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
28069792 MGI
enables nucleoside transmembrane transporter activity IDA
IDA: Inferred from direct assay
11085929 MGI
enables nucleoside transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
35790189 MGI
enables purine nucleoside transmembrane transporter activity IGI
IGI: Inferred from genetic interaction
28069792 MGI
enables purine nucleoside transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
28069792 MGI
enables uridine transmembrane transporter activity IDA
IDA: Inferred from direct assay
11085929 MGI
Biological Process GO Annotation Evidence References Source
involved in adenosine transport IMP
IMP: Inferred from mutant phenotype
28069792 MGI
involved in inosine transport IMP
IMP: Inferred from mutant phenotype
35790189 MGI
involved in neurotransmitter uptake IMP
IMP: Inferred from mutant phenotype
28069792 MGI
involved in nucleoside transmembrane transport IDA
IDA: Inferred from direct assay
11085929 MGI
involved in nucleoside transmembrane transport IMP
IMP: Inferred from mutant phenotype
35790189 MGI
acts upstream of or within nucleoside transport IDA
IDA: Inferred from direct assay
11085929 MGI
involved in nucleoside transport IMP
IMP: Inferred from mutant phenotype
35790189 MGI
involved in purine nucleoside transmembrane transport IMP
IMP: Inferred from mutant phenotype
28069792 MGI
involved in uridine transmembrane transport IDA
IDA: Inferred from direct assay
11085929 MGI
Cellular Component GO Annotation Evidence References Source
is active in plasma membrane IMP
IMP: Inferred from mutant phenotype
28069792 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

equilibrative nucleoside transporter 1

  • NBMPR-sensitive equilibrative nucleoside transporter

  • equilibrative NBMPR-sensitive nucleoside transporter

  • equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter

  • nucleoside transporter, es-type

  • solute carrier family 29 member

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-116927 KW-7158 / Phase 2

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13153 SLC29A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22039 Slc29a1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28556 Slc29a1 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc29a1 NCBI NCBI:2030