2. Gene
  3. Casp7 - caspase 7 Gene

Casp7 - caspase 7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 64026 | Gene type: protein coding

About Casp7

Primary_assembly 1: 255,437,172-255,476,729 forward strand.mRatBN7.2:CM026974.1

This gene has 2 transcripts (splice variants), 218 orthologues, 12 paralogues and is associated with 26 phenotypes. Biased expression in Liver (RPKM 47.5), Heart (RPKM 47.1) and 9 other tissues.

Summary

Enables cysteine-type peptidase activity. Involved in several processes, including aging; leukocyte apoptotic process; and striated muscle cell differentiation. Located in cytosol and intracellular membrane-bounded organelle. Biomarker of several diseases, including endometritis; sciatic neuropathy; transient cerebral ischemia; type 2 diabetes mellitus; and ureteral obstruction. Human ortholog(s) of this gene implicated in Alzheimer's disease; breast cancer; colon cancer; and lung non-small cell carcinoma. Orthologous to human CASP7 (Caspase 7). [provided by Alliance of Genome Resources, Apr 2022]

Casp7 Products(1)

mRNA Protein Name
NM_022260.4 NP_071596.1 caspase-7

Casp7 Protein Structure

CASc

CASc: cd00032 (59 - 300)

  • 0
  • 100
  • 200
  • 303 a.a.
Protein Preferred Names Protein Names

caspase-7

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01962 CASP7 Human Pre-designed siRNA Set A / Unkown
HY-RS01963 Casp7 Mouse Pre-designed siRNA Set A / Unkown
HY-RS01964 Casp7 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Casp7 NCBI NCBI:840