Pdcd4 - programmed cell death 4 Gene

Also Known as Dug

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64031

Summary

Predicted to enable RNA binding activity. Involved in epithelial to mesenchymal transition involved in cardiac fibroblast development; regulation of apoptotic process; and regulation of protein metabolic process. Located in nucleus. Orthologous to human PDCD4 (programmed cell death 4). [provided by Alliance of Genome Resources, Apr 2022]

Pdcd4 Products (1)

mRNA Protein Name
NM_022265.3 NP_071601.2 programmed cell death protein 4

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in epithelial to mesenchymal transition involved in cardiac fibroblast development IGI
IGI: Inferred from genetic interaction
23441172 RGD
involved in negative regulation of apoptotic process IDA
IDA: Inferred from direct assay
12220511 RGD
involved in positive regulation of smooth muscle cell apoptotic process IMP
IMP: Inferred from mutant phenotype
20357187 RGD
involved in regulation of protein metabolic process IMP
IMP: Inferred from mutant phenotype
21406616 RGD
involved in response to alkaloid IEP
IEP: Inferred from expression pattern
30240970 RGD
involved in response to hormone IEP
IEP: Inferred from expression pattern
30240970 RGD
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
23441172 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

programmed cell death protein 4

  • death up-regulated gene protein

  • death-upregulated

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-145232 PhosTAC7 99.23% Unkown
HY-153383 PDCD4-IN-1 Inhibitor 99.41% Unkown
HY-148509 PhosTAC5 98.02% Unkown
HY-148508 PhosTAC3 Inhibitor 99.97% Unkown
HY-RS10192 PDCD4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17345 Pdcd4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23799 Pdcd4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pdcd4 NCBI NCBI:27250