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PhosTAC5 is a phosphorylation targeting chimera (PhosTAC) molecule composed of a linker with fivePEG groups. PhosTAC5 induces dephosphorylation of PDCD4 and FOXO3a.

For research use only. We do not sell to patients.

PhosTAC5 Chemical Structure

PhosTAC5 Chemical Structure

Size Price Stock Quantity
Oil + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 454 In-stock
Solution
10 mM * 1 mL in DMSO USD 454 In-stock
Oil
5 mg USD 250 In-stock
10 mg USD 400 In-stock
25 mg USD 850 In-stock
50 mg USD 1350 In-stock
100 mg USD 1950 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

PhosTAC5 Related Antibodies

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Description

PhosTAC5 is a phosphorylation targeting chimera (PhosTAC) molecule composed of a linker with fivePEG groups. PhosTAC5 induces dephosphorylation of PDCD4 and FOXO3a[1].

Molecular Weight

1031.66

Formula

C54H79ClN2O15
Appearance

Oil

Color

Light yellow to yellow

SMILES

O=C(NCCOCCOCCOCCOCCOCCCCCCCl)COC1=CC=CC([C@H](OC([C@@H]2CCCCN2C([C@H](C3=CC(OC)=C(OC)C(OC)=C3)CC)=O)=O)CCC4=CC(OC)=C(OC)C=C4)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (96.93 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9693 mL 4.8466 mL 9.6931 mL
5 mM 0.1939 mL 0.9693 mL 1.9386 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.9693 mL 4.8466 mL 9.6931 mL 24.2328 mL
5 mM 0.1939 mL 0.9693 mL 1.9386 mL 4.8466 mL
10 mM 0.0969 mL 0.4847 mL 0.9693 mL 2.4233 mL
15 mM 0.0646 mL 0.3231 mL 0.6462 mL 1.6155 mL
20 mM 0.0485 mL 0.2423 mL 0.4847 mL 1.2116 mL
25 mM 0.0388 mL 0.1939 mL 0.3877 mL 0.9693 mL
30 mM 0.0323 mL 0.1616 mL 0.3231 mL 0.8078 mL
40 mM 0.0242 mL 0.1212 mL 0.2423 mL 0.6058 mL
50 mM 0.0194 mL 0.0969 mL 0.1939 mL 0.4847 mL
60 mM 0.0162 mL 0.0808 mL 0.1616 mL 0.4039 mL
80 mM 0.0121 mL 0.0606 mL 0.1212 mL 0.3029 mL
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PhosTAC5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PhosTAC5PhosTAC 5PhosTAC-5OthersInhibitorinhibitorinhibit

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