2. PROTAC
  3. PROTACs
  4. PhosTAC7

Similar to PROTACs in their ability to induce ternary complexes, PhosTAC7 focuses on recruiting a Ser/Thr phosphatase to a phosphosubstrate to mediate its dephosphorylation.

For research use only. We do not sell to patients.

PhosTAC7 Chemical Structure

PhosTAC7 Chemical Structure

CAS No. : 3016307-75-5

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5 mg USD 850 In-stock
10 mg USD 1450 In-stock
25 mg USD 2800 In-stock
50 mg USD 4500 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

PhosTAC7 Related Antibodies

Top Publications Citing Use of Products

View All PROTACs Isoform Specific Products:

View All Isoforms
von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

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  • Purity & Documentation

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Description

Similar to PROTACs in their ability to induce ternary complexes, PhosTAC7 focuses on recruiting a Ser/Thr phosphatase to a phosphosubstrate to mediate its dephosphorylation.

Molecular Weight

1119.77

Formula

C58H87ClN2O17
CAS No.
Appearance

Oil

Color

Colorless to light yellow

SMILES

CC[C@@H](C1=CC(OC)=C(C(OC)=C1)OC)C(N2CCCC[C@H]2C(O[C@@H](C3=CC(OCC(NCCOCCOCCOCCOCCOCCOCCOCCCCCCCl)=O)=CC=C3)CCC4=CC(OC)=C(C=C4)OC)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (89.30 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8930 mL 4.4652 mL 8.9304 mL
5 mM 0.1786 mL 0.8930 mL 1.7861 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.96%

COA (242 KB) HNMR (161 KB) RP-HPLC (407 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.8930 mL 4.4652 mL 8.9304 mL 22.3260 mL
5 mM 0.1786 mL 0.8930 mL 1.7861 mL 4.4652 mL
10 mM 0.0893 mL 0.4465 mL 0.8930 mL 2.2326 mL
15 mM 0.0595 mL 0.2977 mL 0.5954 mL 1.4884 mL
20 mM 0.0447 mL 0.2233 mL 0.4465 mL 1.1163 mL
25 mM 0.0357 mL 0.1786 mL 0.3572 mL 0.8930 mL
30 mM 0.0298 mL 0.1488 mL 0.2977 mL 0.7442 mL
40 mM 0.0223 mL 0.1116 mL 0.2233 mL 0.5582 mL
50 mM 0.0179 mL 0.0893 mL 0.1786 mL 0.4465 mL
60 mM 0.0149 mL 0.0744 mL 0.1488 mL 0.3721 mL
80 mM 0.0112 mL 0.0558 mL 0.1116 mL 0.2791 mL
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PhosTAC7 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PhosTAC73016307-75-5PhosTAC 7PhosTAC-7PROTACsInhibitorinhibitorinhibit

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