2. Gene
  3. ADGRL4 - adhesion G protein-coupled receptor L4 Gene

ADGRL4 - adhesion G protein-coupled receptor L4 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ETL; ELTD1; KPG_003

Gene ID: 64123 | Gene type: protein coding

About ADGRL4

Cytogenetic location: 1p31.1 Genomic coordinates (GRCh38): 1:78,889,764-79,006,730 (from NCBI)

This gene has 17 transcripts (splice variants), 198 orthologues and 42 paralogues. Broad expression in fat (RPKM 38.7), spleen (RPKM 20.4) and 20 other tissues.

Summary

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in cytoplasmic vesicle and plasma membrane. Predicted to be integral component of plasma membrane. Biomarker of glioblastoma and hypertrophic cardiomyopathy. [provided by Alliance of Genome Resources, Apr 2022]

ADGRL4 Products(1)

mRNA Protein Name
NM_022159.4 NP_071442.2 adhesion G protein-coupled receptor L4 precursor

ADGRL4 Protein Structure

EGF_CA

EGF_CA: Calcium-binding EGF domain (58 - 94)

(131 - 343)

GPS

GPS: GPCR proteolysis site, GPS, motif (368 - 413)

7tm_2

7tm_2: 7 transmembrane receptor (Secretin family) (427 - 660)

  • 0
  • 200
  • 400
  • 600
  • 690 a.a.
Protein Preferred Names Protein Names

adhesion G protein-coupled receptor L4

EGF, latrophilin and seven transmembrane domain containing 1

Related Diseases

Diseases Alias
Transient Refractive Change
Volkmann Contracture

Ischemic Contracture

Volkmann'S Ischemic Contracture
Usher Syndrome, Type Iic

Usher Syndrome Type 2c

USH2C

Usher Syndrome, Type 2c

Usher Syndrome, Type Iic, Gpr98/Pdzd7 Digenic

Usher Syndrome Type Iic

Usher Syndrome, Type 2c, Gpr98/Pdzd7 Digenic

Usher Syndrome 2c

Usher'S Syndrome Type 2c

Usher Syndrome Type Iic Gpr98/Pdzd7 Digenic
Idh-Wildtype Anaplastic Astrocytoma
Tympanosclerosis

Ts - [Tympanosclerosis]

Tympanic Membrane Sclerosis
Tympanic Membrane Disease

Disorder Of Tympanic Membrane
Glioblastoma

Glioblastoma Multiforme

Gbm

Adult Glioblastoma Multiforme

Grade Iv Adult Astrocytic Tumor

Primary Glioblastoma Multiforme

Spongioblastoma Multiforme

Adult Glioblastoma

Primary Glioblastoma
Hypertrophic Cardiomyopathy

Hypertrophic Obstructive Cardiomyopathy

Cardiomyopathy, Hypertrophic

Cardiomyopathy Hypertrophic Obstructive

Cardiomyopathy, Hypertrophic, Familial

Idiopathic Myocardial Hypertrophy

Idiopathic Hypertrophic Cardiomyopathy

Obstructive Idiopathic Hypertrophic Cardiomyopathy

Obstructive Cardiomyopathy

Idiopathic Hypertrophic Subaortic Stenosis

Muscular Subaortic Stenosis

Hypertrophic Obstructive Subaortic Stenosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00364 ADGRL4 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ADGRL4 MGD MGI:2655562
Rattus norvegicus ADGRL4 RGD RGD:621136
Macaca mulatta ADGRL4 VGNC VGNC:69652
Canis familiaris ADGRL4 VGNC VGNC:37653
Felis catus ADGRL4 VGNC VGNC:59640
Bos taurus ADGRL4 VGNC VGNC:25672