ADGRL4 - adhesion G protein-coupled receptor L4 Gene

Also Known as ETL; ELTD1; KPG_003

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 64123

About ADGRL4

Cytogenetic location: 1p31.1 Genomic coordinates (GRCh38): 1:78,889,764-79,006,730 (from NCBI)

This gene has 17 transcripts (splice variants), 198 orthologues and 42 paralogues. Broad expression in fat (RPKM 38.7), spleen (RPKM 20.4) and 20 other tissues.

Summary

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in cytoplasmic vesicle and plasma membrane. Predicted to be integral component of plasma membrane. Biomarker of glioblastoma and hypertrophic cardiomyopathy. [provided by Alliance of Genome Resources, Apr 2022]

ADGRL4 Products (1)

mRNA	Protein	Name
NM_022159.4	NP_071442.2	adhesion G protein-coupled receptor L4 precursor

ADGRL4 Protein Structure

EGF_CA

GPS

7tm_2

0
200
400
600
690 a.a.

Protein Preferred Names	Protein Names
adhesion G protein-coupled receptor L4	EGF, latrophilin and seven transmembrane domain containing 1

Related Diseases

Diseases	Alias
Transient Refractive Change
Volkmann Contracture	Ischemic Contracture Volkmann'S Ischemic Contracture
Usher Syndrome, Type Iic	Usher Syndrome Type 2c USH2C Usher Syndrome, Type 2c Usher Syndrome, Type Iic, Gpr98/Pdzd7 Digenic Usher Syndrome Type Iic Usher Syndrome, Type 2c, Gpr98/Pdzd7 Digenic Usher Syndrome 2c Usher'S Syndrome Type 2c Usher Syndrome Type Iic Gpr98/Pdzd7 Digenic
Idh-Wildtype Anaplastic Astrocytoma
Tympanosclerosis	Ts - [Tympanosclerosis] Tympanic Membrane Sclerosis
Tympanic Membrane Disease	Disorder Of Tympanic Membrane
Glioblastoma	Glioblastoma Multiforme Gbm Adult Glioblastoma Multiforme Grade Iv Adult Astrocytic Tumor Primary Glioblastoma Multiforme Spongioblastoma Multiforme Adult Glioblastoma Primary Glioblastoma
Hypertrophic Cardiomyopathy	Hypertrophic Obstructive Cardiomyopathy Cardiomyopathy, Hypertrophic Cardiomyopathy Hypertrophic Obstructive Cardiomyopathy, Hypertrophic, Familial Idiopathic Myocardial Hypertrophy Idiopathic Hypertrophic Cardiomyopathy Obstructive Idiopathic Hypertrophic Cardiomyopathy Obstructive Cardiomyopathy Idiopathic Hypertrophic Subaortic Stenosis Muscular Subaortic Stenosis Hypertrophic Obstructive Subaortic Stenosis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00364	ADGRL4 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	ADGRL4	MGD	MGI:2655562
Rattus norvegicus	ADGRL4	RGD	RGD:621136
Macaca mulatta	ADGRL4	VGNC	VGNC:69652
Canis familiaris	ADGRL4	VGNC	VGNC:37653
Felis catus	ADGRL4	VGNC	VGNC:59640
Bos taurus	ADGRL4	VGNC	VGNC:25672
Others	ADGRL4	NCBI