2. Gene
  3. SH3BGR - SH3 domain binding glutamate rich protein Gene

SH3BGR - SH3 domain binding glutamate rich protein Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as 21-GARP

Gene ID: 6450 | Gene type: protein coding

About SH3BGR

Cytogenetic location: 21q22.2 Genomic coordinates (GRCh38): 21:39,445,865-39,515,506 (from NCBI)

This gene has 10 transcripts (splice variants), 190 orthologues and 3 paralogues. Biased expression in heart (RPKM 36.2), prostate (RPKM 11.6) and 10 other tissues.

Summary

Predicted to enable SH3 domain binding activity. Predicted to be involved in protein-containing complex assembly. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

SH3BGR Products(5)

mRNA Protein Name
NM_001001713.1 NP_001001713.1 SH3 domain-binding glutamic acid-rich protein isoform b
NM_001317740.2 NP_001304669.2 SH3 domain-binding glutamic acid-rich protein isoform c
NM_001317741.1 NP_001304670.1 SH3 domain-binding glutamic acid-rich protein isoform d
NM_001317742.1 NP_001304671.1 SH3 domain-binding glutamic acid-rich protein isoform b
NM_007341.3 NP_031367.2 SH3 domain-binding glutamic acid-rich protein isoform a

SH3BGR Protein Structure

SH3BGR

SH3BGR: SH3-binding, glutamic acid-rich protein (64 - 161)

  • 0
  • 100
  • 200
  • 239 a.a.
Protein Preferred Names Protein Names

SH3 domain-binding glutamic acid-rich protein

SH3-binding domain and glutamic acid-rich protein

Related Diseases

Diseases Alias
Down Syndrome

Trisomy 21

Complete Trisomy 21 Syndrome

Down'S Syndrome

Trisomy 21 Syndrome

Down'S Syndrome - Trisomy 21

Downs Syndrome

G Trisomy

47,Xx,+21

47,Xy,+21

Trisomy G

Down Syndrome, Susceptibility To

Chromosome 21 Trisomy

Trisomy 21 Nos

Abnormal Autosomes 21
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12826 SH3BGR Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta SH3BGR VGNC VGNC:77199
Bos taurus SH3BGR VGNC VGNC:34563
Felis catus SH3BGR VGNC VGNC:102841
Mus musculus SH3BGR MGD MGI:1354740
Rattus norvegicus SH3BGR RGD RGD:1563599