2. Gene
  3. DCP1B - decapping mRNA 1B Gene

DCP1B - decapping mRNA 1B Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as DCP1

Gene ID: 196513 | Gene type: protein coding

About DCP1B

Cytogenetic location: 12p13.33 Genomic coordinates (GRCh38): 12:1,941,591-2,004,457 (from NCBI)

This gene has 7 transcripts (splice variants), 1 gene allele, 212 orthologues and 1 paralogue. Broad expression in testis (RPKM 7.9), endometrium (RPKM 5.4) and 25 other tissues.

Summary

This gene encodes a member of a family of proteins that function in removing the 5' cap from mRNAs, which is a step in regulated mRNA decay. This protein localizes to cytoplasmic foci which are the site of mRNA breakdown and turnover. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

DCP1B Products(2)

mRNA Protein Name
NM_001319292.2 NP_001306221.1 mRNA-decapping enzyme 1B isoform 2
NM_152640.5 NP_689853.3 mRNA-decapping enzyme 1B isoform 1

DCP1B Protein Structure

DCP1

DCP1: Dcp1-like decapping family (13 - 130)

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  • 617 a.a.
Protein Preferred Names Protein Names

mRNA-decapping enzyme 1B

DCP1 decapping enzyme homolog B

Related Diseases

Diseases Alias
Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip/Palate Syndrome 3

Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip-Palate Syndrome 3

EEC3

Eec Syndrome 3

Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip/Palate Syndrome, Type 3
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03585 DCP1B Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris DCP1B VGNC VGNC:39809
Rattus norvegicus DCP1B RGD RGD:1562214
Macaca mulatta DCP1B VGNC VGNC:71699
Felis catus DCP1B VGNC VGNC:61373
Bos taurus DCP1B VGNC VGNC:27920
Mus musculus DCP1B MGD MGI:2442404