SLC20A1 - solute carrier family 20 member 1 Gene

Homo sapiens

Also known as PIT1; GLVR1; PiT-1; Glvr-1

Gene ID: 6574 | Gene type: protein coding

About SLC20A1

Cytogenetic location: 2q14.1 Genomic coordinates (GRCh38): 2:112,645,939-112,663,825 (from NCBI)

This gene has 9 transcripts (splice variants), 288 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 15.0), colon (RPKM 14.5) and 24 other tissues.

Summary

The protein encoded by this gene is a sodium-phosphate symporter that absorbs phosphate from interstitial fluid for use in cellular functions such as metabolism, signal transduction, and nucleic acid and lipid synthesis. The encoded protein is also a retroviral receptor, causing human cells to be susceptible to Infection by gibbon ape leukemia virus, simian sarcoma-associated virus, feline leukemia virus subgroup B, and 10A1 murine leukemia virus.[provided by RefSeq, Mar 2011]

SLC20A1 Products(1)

mRNA	Protein	Name
NM_005415.5	NP_005406.3	sodium-dependent phosphate transporter 1

SLC20A1 Protein Structure

PHO4

0
200
400
600
679 a.a.

Protein Preferred Names

Protein Names

sodium-dependent phosphate transporter 1

gibbon ape leukemia virus receptor 1

Related Diseases

Diseases

Alias

Leukemia

Leukemias	Leukaemia, Unspecified, Without Mention Of Remission
Aleukemic Leukaemia	Chronic Leukaemia
Subacute Leukaemia	Leukaemia Disorder
Leukaemia Nos

Hyperphosphatemia

Cloacal Exstrophy

Oeis Complex	Omphalocele-Cloacal Exstrophy-Imperforate Anus-Spinal Defect Syndrome
Omphalocele, Exstrophy Of The Cloaca, Imperforate Anus, And Spinal Defects Compl	Omphalocele, Exstrophy Of The Cloaca, Imperforate Anus, And Spinal Defects Complex
Cloacal Exstrophy Sequence	Omphalocele - Cloacal Exstrophy - Imperforate Anus - Spinal Defect
Omphalocele, Exstrophy Of The Cloaca, Imperforate Anus, And Spinal Defects	Omphalocele Exstrophy Imperforate Anus

Sarcoma

Connective And Soft Tissue Neoplasm	Tumor Of Soft Tissue And Skeleton
Sarcomas	Sarcoma - Category

Bladder Exstrophy-Epispadias-Cloacal Exstrophy Complex

Exstrophy-Epispadias Complex	Bladder Exstrophy-Epispadias-Cloacal Extrophy Complex
Beec	Eec
Exstrophy Of The Bladder	Bladder Exstrophy
Bladder Exstrophy And Epispadias Complex

Pulmonary Alveolar Microlithiasis

PULAM

Pam

Ureterocele

Calcification Of Joints And Arteries

Hereditary Arterial And Articular Multiple Calcification Syndrome	CALJA
Arterial Calcification Due To Cd73 Deficiency	Arterial Calcification Due To Deficiency Of Cd73
Acdc	Arterial Calcification And Distal Joint Calcification
Arterial Calcification Due To Deficiency Of Cd73:Acdc	Calcification Of Joints And Arteries
Calja

Basal Ganglia Disease

Basal Ganglia Diseases	Basal Ganglia Disorders
Abnormality Of The Basal Ganglia

Bladder Exstrophy

Exstrophy Of The Bladder

Classic Exstrophy Of The Bladder

Basal Ganglia Calcification

Fahr'S Syndrome	Fahr'S Disease
Fahr Disease

Severe Congenital Neutropenia 4

Autosomal Recessive Severe Congenital Neutropenia Due To G6pc3 Deficiency	Scn4
Severe Congenital Neutropenia-Pulmonary Hypertension-Superficial Venous Angiectasis Syndrome	Dursun Syndrome
Severe Congenital Neutropenia Type 4

Periarthritis

Phosphorus Metabolism Disease

Phosphorus Metabolism Disorders	Disorder Of Phosphorus Metabolism
Phosphorus Disorder	Phosphorus Metabolism Disorder

Anus, Imperforate

Imperforate Anus	Anorectal Malformation
Anal Atresia	Anorectal Malformations
Congenital Atresia Of Anus	Congenital Or Infantile Occlusion Of Anus
Anal Stenosis	Arm

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13059	SLC20A1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	SLC20A1	VGNC	VGNC:34717
Felis catus	SLC20A1	VGNC	VGNC:65236
Canis familiaris	SLC20A1	VGNC	VGNC:46268
Mus musculus	SLC20A1	MGD	MGI:108392
Macaca mulatta	SLC20A1	VGNC	VGNC:77415
Rattus norvegicus	SLC20A1	RGD	RGD:621079

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