STK33 - serine/threonine kinase 33 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 65975

About STK33

Cytogenetic location: 11p15.4 Genomic coordinates (GRCh38): 11:8,334,824-8,594,228 (from NCBI)

This gene has 18 transcripts (splice variants), 189 orthologues and 22 paralogues. Biased expression in testis (RPKM 7.0), thyroid (RPKM 2.1) and 11 other tissues.

Summary

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in mitotic DNA damage checkpoint signaling and protein autophosphorylation. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

STK33 Products (17)

mRNA Protein Name
NM_001289058.2 NP_001275987.1 serine/threonine-protein kinase 33 isoform b
NM_001289059.2 NP_001275988.1 serine/threonine-protein kinase 33 isoform c
NM_001289061.2 NP_001275990.1 serine/threonine-protein kinase 33 isoform a
NM_001352387.2 NP_001339316.1 serine/threonine-protein kinase 33 isoform a
NM_001352388.2 NP_001339317.1 serine/threonine-protein kinase 33 isoform a
NM_001352389.2 NP_001339318.1 serine/threonine-protein kinase 33 isoform a
NM_001352390.2 NP_001339319.1 serine/threonine-protein kinase 33 isoform a
NM_001352391.2 NP_001339320.1 serine/threonine-protein kinase 33 isoform a
NM_001352392.2 NP_001339321.1 serine/threonine-protein kinase 33 isoform a
NM_001352393.2 NP_001339322.1 serine/threonine-protein kinase 33 isoform a
NM_001352394.2 NP_001339323.1 serine/threonine-protein kinase 33 isoform b
NM_001352395.2 NP_001339324.1 serine/threonine-protein kinase 33 isoform b
NM_001352396.2 NP_001339325.1 serine/threonine-protein kinase 33 isoform d
NM_001352397.2 NP_001339326.1 serine/threonine-protein kinase 33 isoform d
NM_001352398.2 NP_001339327.1 serine/threonine-protein kinase 33 isoform d
NM_001352399.2 NP_001339328.1 serine/threonine-protein kinase 33 isoform e
NM_030906.4 NP_112168.1 serine/threonine-protein kinase 33 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein serine/threonine kinase activity IMP
IMP: Inferred from mutant phenotype
37146716 GOA
Biological Process GO Annotation Evidence References Source
involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
37146716 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

STK33 Protein Structure

Pkinase

Pkinase: Protein kinase domain (116 - 381)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 514 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein kinase 33

STK33 Antibodies

Cat. No. Product Name Application Reactivity
HY-P82340 STK33 Antibody (YA2085) WB, IHC-F, IHC-P, ICC/IF Human
HY-P82340A STK33 Antibody (YA2085)(PBS only) WB, IHC-F, IHC-P, ICC/IF Human

Related Diseases

Diseases Alias
Pancreatic Cancer

  • Pancreatic Carcinoma

  • Carcinoma Of Pancreas

  • Familial Pancreatic Carcinoma

  • Pancreatic Neoplasm

  • Pancreatic Carcinoma, Familial

  • Malignant Neoplasm Of Pancreas

  • Pancreatic Acinar Carcinoma

  • Pancreatic Tumor

  • Familial Pancreatic Cancer

  • Neoplasm Of The Pancreas

  • Cancer Of The Pancreas

  • Pancreatic Carcinoma, Somatic

  • Pancreatic Cancer, Somatic

  • Ca Body Of Pancreas

  • Ca Head Of Pancreas

  • Ca Tail Of Pancreas

  • Malignant Neoplasm Of Body Of Pancreas

  • Malignant Neoplasm Of Head Of Pancreas

  • Malignant Neoplasm Of Tail Of Pancreas

  • Pancreas Neoplasm

  • Exocrine Cancer

  • Exocrine Pancreas Carcinoma

  • Hereditary Pancreatic Cancer

  • Hereditary Pancreatic Carcinoma

  • PNCA

  • Pancreatic Cancer, Susceptibility To

  • Carcinoma Of Head Of Pancreas

  • Pancreatic Neoplasms

  • Pancreatic Tumors

  • Cancer, Pancreatic

  • Cancer Of Pancreas

  • Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Tyrosinemia, Type Iii

  • Tyrosinemia Type Iii

  • 4-Hydroxyphenylpyruvate Dioxygenase Deficiency

  • TYRSN3

  • 4-Hydroxyphenylpyruvic Acid Oxidase Deficiency

  • Tyrosinemia Type 3

  • 4-Alpha Hydroxyphenylpyruvate Dioxygenase Deficiency

  • 4-Alpha Hydroxyphenylpyruvic Acid Oxidase Deficiency

  • Tyrosinemia Due To 4-Hydroxyphenylpyruvate Dioxygenase Deficiency

  • Tyrosinemia Due To 4-Hydroxyphenylpyruvic Acid Oxidase Deficiency

  • Tyrosinemia Due To Hpd Deficiency

  • Tyrosinemia 3
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13495 ML281 Inhibitor 98.04% Unkown
HY-162565 CDD-2807 Inhibitor 99.52% Unkown
HY-114331 DLK-IN-1 Inhibitor 98.27% Unkown
HY-13498 BRD-8899 Inhibitor / Unkown
HY-13497 STK33-IN-1 Inhibitor / Unkown
HY-176885 CDD-2211 Inhibitor / Unkown
HY-176885A CDD-2212 Inhibitor / Unkown
HY-176884 CDD-2110 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus STK33 RGD RGD:1590972
Felis catus STK33 VGNC VGNC:65783
Bos taurus STK33 VGNC VGNC:35396
Macaca mulatta STK33 VGNC VGNC:78118
Mus musculus STK33 MGD MGI:2152419
Canis familiaris STK33 VGNC VGNC:46916
Others STK33 NCBI