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ML281 

Cat. No.: HY-13495 Purity: 99.65%
Data Sheet SDS Handling Instructions

ML281 is a potent and selective STK33 inhibitor with IC50 of 14 nM.

For research use only. We do not sell to patients.
ML281 Chemical Structure

ML281 Chemical Structure

CAS No. : 1404437-62-2

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Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO $99 In-stock
5 mg $90 In-stock
10 mg $120 In-stock
50 mg $450 In-stock
100 mg $750 In-stock
200 mg $1100 In-stock
500 mg   Get quote  
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Description

ML281 is a potent and selective STK33 inhibitor with IC50 of 14 nM. ML281 showed a 550-fold selectivity over AurB and greater than 700-fold selectivity over PKA. target: STK33 IC50: 14 nM [1] ML281 showed low nanomolar inhibition of purified recombinant STK33 and a distinct selectivity profile as compared to other STK33 inhibitors. Even at the highest concentration tested (10 μM), ML281 had no effect on the viability of KRAS-dependent cancer cells. [2]

References
Molecular Weight

389.47

Formula

C₂₂H₁₉N₃O₂S

CAS No.

1404437-62-2

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 30 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
ML281
Cat. No.:
HY-13495
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