CHID1 - chitinase domain containing 1 Gene

Also Known as GL008; SICLP; SI-CLP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 66005

About CHID1

Cytogenetic location: 11p15.5 Genomic coordinates (GRCh38): 11:867,859-915,214 (from NCBI)

This gene has 24 transcripts (splice variants), 191 orthologues and 6 paralogues. Ubiquitous expression in testis (RPKM 12.9), spleen (RPKM 11.8) and 25 other tissues.

Summary

Enables oligosaccharide binding activity. Involved in negative regulation of cytokine production involved in inflammatory response. Located in several cellular components, including late endosome; lysosome; and trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2022]

CHID1 Products (5)

mRNA Protein Name
NM_001142674.2 NP_001136146.1 chitinase domain-containing protein 1 isoform a precursor
NM_001142675.2 NP_001136147.1 chitinase domain-containing protein 1 isoform a precursor
NM_001142676.2 NP_001136148.1 chitinase domain-containing protein 1 isoform b precursor
NM_001142677.2 NP_001136149.1 chitinase domain-containing protein 1 isoform c precursor
NM_023947.4 NP_076436.3 chitinase domain-containing protein 1 isoform a precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables oligosaccharide binding IPI
IPI: Inferred from physical interaction
20724479 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
16357325 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of cytokine production involved in inflammatory response IDA
IDA: Inferred from direct assay
20724479 GOA
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
16357325 GOA
located in late endosome IDA
IDA: Inferred from direct assay
16357325 GOA
located in lysosome IDA
IDA: Inferred from direct assay
16357325 GOA
located in trans-Golgi network IDA
IDA: Inferred from direct assay
16357325 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CHID1 Protein Structure

Glyco_hydro_18

Glyco_hydro_18: Glycosyl hydrolases family 18 (81 - 384)

  • 0
  • 100
  • 200
  • 300
  • 393 a.a.
Protein Preferred Names Protein Names

chitinase domain-containing protein 1

  • stabilin-1 interacting chitinase-like protein

Recombinant CHID1 Proteins

Cat. No. Product Name Accession Purity
HY-P71647 CHID1 Protein, Human (His) Q9BWS9-1 (T20-L393) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02631 CHID1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22437 Chid1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28960 Chid1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CHID1 VGNC VGNC:27294
Felis catus CHID1 VGNC VGNC:60858
Canis familiaris CHID1 VGNC VGNC:39217
Rattus norvegicus CHID1 RGD RGD:1308955
Macaca mulatta CHID1 VGNC VGNC:71123
Mus musculus CHID1 MGD MGI:1915288
Others CHID1 NCBI