Ptpmt1 - protein tyrosine phosphatase, mitochondrial 1 Gene

Also Known as PLIP; 1110001D10Rik; 2810004N20Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66461

Summary

Enables phosphatidylglycerophosphatase activity and phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. Involved in cardiolipin biosynthetic process. Located in mitochondrion. Is expressed in several structures, including genitourinary system; gut; immune system; inner cell mass; and musculature. Orthologous to human PTPMT1 (protein tyrosine Phosphatase mitochondrial 1). [provided by Alliance of Genome Resources, Apr 2022]

Ptpmt1 Products (2)

mRNA Protein Name
NM_025576.2 NP_079852.1 phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
NM_025576.2 NP_079852.1 phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables phosphatidylglycerophosphatase activity EXP
EXP: Inferred from Experiment
21641550 MGI
enables phosphatidylglycerophosphatase activity IMP
IMP: Inferred from mutant phenotype
21641550 MGI
enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IDA
IDA: Inferred from direct assay
15247229 MGI
Biological Process GO Annotation Evidence References Source
involved in cardiolipin biosynthetic process IMP
IMP: Inferred from mutant phenotype
21641550 MGI
Cellular Component GO Annotation Evidence References Source
is active in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
16039589 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

  • PTEN-like phosphatase

  • phosphoinositide lipid phosphatase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-108547 Alexidine dihydrochloride 99.68% Unkown
HY-B1474 Alexidine Inhibitor / Unkown
HY-RS11414 PTPMT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-B1474S1 Alexidine-d10 Inhibitor / Unkown
HY-RS18311 Ptpmt1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24789 Ptpmt1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptpmt1 NCBI NCBI:114971