Kmt5a - lysine methyltransferase 5A Gene
Also Known as Setd8; PR-SET7; PR/SET07; 2410195B05Rik
Species: Mus musculus
Summary
Predicted to enable histone-lysine N-methyltransferase activity; p53 binding activity; and transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; peptidyl-lysine monomethylation; and regulation of DNA damage response, signal transduction by p53 class mediator. Predicted to act upstream of or within cell division; chromatin organization; and methylation. Predicted to be located in cytosol and nucleoplasm. Is expressed in embryo. Orthologous to human KMT5A (lysine methyltransferase 5A). [provided by Alliance of Genome Resources, Apr 2022]
Kmt5a Products (6)
| mRNA | Protein | Name |
|---|---|---|
| NM_001310723.2 | NP_001297652.1 | N-lysine methyltransferase KMT5A isoform 2 |
| NM_001310725.2 | NP_001297654.1 | N-lysine methyltransferase KMT5A isoform 3 |
| NM_001310727.2 | NP_001297656.1 | N-lysine methyltransferase KMT5A isoform 3 |
| NM_001405388.1 | NP_001392317.1 | N-lysine methyltransferase KMT5A isoform 3 |
| NM_001405390.1 | NP_001392319.1 | N-lysine methyltransferase KMT5A isoform 4 |
| NM_030241.4 | NP_084517.2 | N-lysine methyltransferase KMT5A isoform 1. |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
N-lysine methyltransferase KMT5A |
|
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Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-12335 | UNC0379 | Inhibitor | 99.17% | Unkown |
| HY-100625 | BVT948 | Inhibitor | ≥99.0% | Unkown |
| HY-12335A | UNC0379 TFA | Inhibitor | 99.91% | Unkown |
| HY-RS07406 | KMT5A Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS18288 | Kmt5a Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS24766 | Kmt5a Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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