Ndufa4 - Ndufa4, mitochondrial complex associated Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 681024

Summary

Predicted to be involved in positive regulation of cytochrome-c oxidase activity. Part of mitochondrial respiratory chain complex I and mitochondrial respiratory chain complex IV. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to human NDUFA4 (NDUFA4 mitochondrial complex associated). [provided by Alliance of Genome Resources, Apr 2022]

Ndufa4 Products (1)

mRNA Protein Name
NM_001127684.2 NP_001121156.1 cytochrome c oxidase subunit NDUFA4

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
part of respiratory chain complex I IDA
IDA: Inferred from direct assay
30361421 RGD
part of respiratory chain complex IV IDA
IDA: Inferred from direct assay
30361421 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytochrome c oxidase subunit NDUFA4

  • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4

  • NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4

  • NADH:ubiquinone oxidoreductase subunit A4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09130 NDUFA4L2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09129 NDUFA4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19794 Ndufa4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26290 Ndufa4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ndufa4 NCBI NCBI:4697