Rrm1 - ribonucleotide reductase catalytic subunit M1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 685579

Summary

Predicted to enable several functions, including ATP binding activity; disordered domain specific binding activity; and identical protein binding activity. Involved in several processes, including animal organ development; pyrimidine nucleobase metabolic process; and response to ionizing radiation. Located in several cellular components, including cell projection; neuronal cell body; and nuclear envelope. Biomarker of visual epilepsy. Orthologous to human RRM1 (ribonucleotide reductase catalytic subunit M1). [provided by Alliance of Genome Resources, Apr 2022]

Rrm1 Products (1)

mRNA Protein Name
NM_001013236.1 NP_001013254.1 ribonucleoside-diphosphate reductase large subunit

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Références Source
involved in cell proliferation in forebrain IEP
IEP: Inferred from expression pattern
12834878 RGD
involved in male gonad development IEP
IEP: Inferred from expression pattern
2775821 RGD
involved in pyrimidine nucleobase metabolic process IEP
IEP: Inferred from expression pattern
10204803 RGD
involved in response to ionizing radiation IEP
IEP: Inferred from expression pattern
19444910 RGD
involved in retina development in camera-type eye IEP
IEP: Inferred from expression pattern
2647502 RGD
Cellular Component GO Annotation Evidence Références Source
located in cell projection IDA
IDA: Inferred from direct assay
15725396 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
12834878 RGD
located in nuclear envelope IDA
IDA: Inferred from direct assay
2205248 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ribonucleoside-diphosphate reductase large subunit

  • ribonucleotide reductase M1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-N0527 Pentagalloylglucose 99.57% Unkown
HY-P5960 PTBP1-RNA-binding inhibitor P6 TFA 98.59% Unkown
HY-153898 rTRD01 Ligand 99.10% Unkown
HY-153736 NSC 194308 99.86% Unkown
HY-RS12285 RRM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18637 Rrm1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25122 Rrm1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rrm1 NCBI NCBI:6240