Dtx1 - deltex E3 ubiquitin ligase 1 Gene

Predicted to enable Notch binding activity; ubiquitin protein Ligase activity; and ubiquitin protein Ligase binding activity. Predicted to be involved in several processes, including Notch signaling pathway; negative regulation of neuron differentiation; and regulation of Notch signaling pathway. Predicted to act upstream of or within cellular response to leukemia inhibitory factor; glial cell differentiation; and negative regulation of T cell differentiation. Predicted to be located in cytosol and nuclear body. Predicted to be active in nucleoplasm. Orthologous to human DTX1 (deltex E3 ubiquitin Ligase 1). [provided by Alliance of Genome Resources, Apr 2022]