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Cat. No.: HY-126931

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Dinophysistoxin 1

(Synonyms: DTX 1)

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Dinophysistoxin 1 (DTX 1, 35-methylokadaic acid) is a causative agent of diarrhetic shellfish poisoning. Dinophysistoxin 1 exerts tumor-promoting activity, serves as a skin irritant as well.

For research use only. We do not sell to patients.

Purity: 95.00%
CAS No.: 81720-10-7
Formula: C₄₅H₇₀O₁₃
Molecular Weight:819.03

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Dinophysistoxin 1 Chemical Structure

CAS No.: 81720-10-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Dinophysistoxin 1 (DTX 1, 35-methylokadaic acid) is a causative agent of diarrhetic shellfish poisoning. Dinophysistoxin 1 exerts tumor-promoting activity, serves as a skin irritant as well^[1].

All Endogenous Metabolite Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
L1210	IC₅₀	2 ng/mL Compound: 2	Cytotoxicity against mouse L1210 cells Cytotoxicity against mouse L1210 cells	[PMID: 7623052]

In Vitro

Dinophysistoxin 1 inhibits the specific [3H]okadaic acid binding to a particulate fraction of mouse epidermis^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Dinophysistoxin 1 (5 μg/mouse; application on the back; twice weekly for 30 weeks) increases the percentages of tumor-bearing mice in the groups treated with 100 μg 7,12-dimethylbenz[a]anthracene (DMBA)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 81720-10-7
Appearance Solid
Molecular Weight 819.03
Formula C₄₅H₇₀O₁₃
Color Off-white to light yellow
SMILES

OC([C@@](O)(C)C[C@H](CC[C@H]1O)O[C@@]1(O2)C=C(C)C[C@@]2([H])[C@H](C)/C=C/[C@H](O3)CC[C@@]3(O4)CC[C@@]([C@]4([H])[C@H](O)C5=C)([H])O[C@]5([H])[C@@H](O)C[C@H](C)[C@@]([C@H](C)CC6)([H])O[C@@]76OCCC[C@H]7C)=O
Synonyms

DTX 1
Structure Classification
- Terpenoids
- Other Terpenoids
Initial Source
- Animals
Mytilus edulis
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Fujiki H, et al. Diarrhetic shellfish toxin, dinophysistoxin-1, is a potent tumor promoter on mouse skin. Jpn J Cancer Res. 1988 Oct;79(10):1089-93. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References

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Dinophysistoxin 1

All Endogenous Metabolite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Dinophysistoxin 1 Related Classifications

HY-126931 Related Classifications