Wdfy1 - WD repeat and FYVE domain containing 1 Gene

Also Known as Jr1; WDF1; FENS-1; ZFYVE17; mKIAA1435; 1700013B03Rik; 1700120F24Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69368

Summary

Predicted to enable 1-phosphatidylinositol binding activity. Involved in positive regulation of Toll-like Receptor 3 signaling pathway and positive regulation of Toll-like Receptor 4 signaling pathway. Located in early endosome. Is expressed in extraembryonic component; placenta; and skin. Orthologous to human WDFY1 (WD repeat and FYVE domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Wdfy1 Products (2)

mRNA Protein Name
NM_001111279.1 NP_001104749.1 WD repeat and FYVE domain-containing protein 1 isoform 1
NM_027057.3 NP_081333.1 WD repeat and FYVE domain-containing protein 1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25736436 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of toll-like receptor 3 signaling pathway IMP
IMP: Inferred from mutant phenotype
25736436 MGI
involved in positive regulation of toll-like receptor 4 signaling pathway IMP
IMP: Inferred from mutant phenotype
25736436 MGI
Cellular Component GO Annotation Evidence References Source
located in early endosome IDA
IDA: Inferred from direct assay
25736436 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

WD repeat and FYVE domain-containing protein 1

  • WD40 and FYVE domain containing 1

  • WD40- and FYVE domain-containing protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15754 WDFY1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22918 Wdfy1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29432 Wdfy1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Wdfy1 NCBI NCBI:57590