Treml1 - triggering receptor expressed on myeloid cells-like 1 Gene

Also Known as TLT-1; 5430401J17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 71326

Summary

Predicted to enable transmembrane signaling receptor activity. Acts upstream of or within platelet activation. Located in cell surface and platelet alpha granule. Is expressed in liver lobe and testis. Orthologous to human TREML1 (triggering receptor expressed on myeloid cells like 1). [provided by Alliance of Genome Resources, Apr 2022]

Treml1 Products (3)

mRNA Protein Name
NM_001289451.1 NP_001276380.1 trem-like transcript 1 protein isoform 2 precursor
NM_001289457.1 NP_001276386.1 trem-like transcript 1 protein isoform 3 precursor
NM_027763.2 NP_082039.1 trem-like transcript 1 protein isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12393607 MGI
Biological Process GO Annotation Evidence References Source
involved in platelet activation IEP
IEP: Inferred from expression pattern
15100151 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
15100151 MGI
located in platelet alpha granule IDA
IDA: Inferred from direct assay
15100151 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

trem-like transcript 1 protein

  • triggering receptor expressed on myeloid cells-like 1c

  • triggering receptor expressed on myeloid cells-like 1d

  • triggering receptor expressed on myeloid cells-like 1e

  • triggering receptor expressed on myeloid cells-like protein 1

Recombinant Treml1 Proteins

Cat. No. Product Name Accession Purity
HY-P700836 TREML1 Protein, Mouse (HEK293, hFc) Q8K558-2/AAL85488.1 (D21-Q175) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P991029 Sutacimig Activator 99.08% Phase 2

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15004 TREML1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20608 Treml1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27116 Treml1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Treml1 NCBI NCBI:340205