Fbxo22 - F-box protein 22 Gene

Also Known as 0610033L19Rik; 1600016C16Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 71999

Summary

Acts upstream of or within several processes, including positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; and regulation of skeletal muscle fiber development. Located in cytoplasm and nucleus. Orthologous to human FBXO22 (F-box protein 22). [provided by Alliance of Genome Resources, Apr 2022]

Fbxo22 Products (2)

mRNA Protein Name
NM_028049.2 NP_082325.2 F-box only protein 22
NM_028049.2 NP_082325.2 F-box only protein 22

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19319192 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to starvation IDA
IDA: Inferred from direct assay
19319192 MGI
acts upstream of or within nucleocytoplasmic transport IDA
IDA: Inferred from direct assay
19319192 MGI
acts upstream of or within positive regulation of proteasomal ubiquitin-dependent protein catabolic process IMP
IMP: Inferred from mutant phenotype
19319192 MGI
acts upstream of or within positive regulation of ubiquitin-dependent protein catabolic process IMP
IMP: Inferred from mutant phenotype
19319192 MGI
acts upstream of proteasome-mediated ubiquitin-dependent protein catabolic process IMP
IMP: Inferred from mutant phenotype
19319192 MGI
acts upstream of or within protein polyubiquitination IDA
IDA: Inferred from direct assay
19319192 MGI
acts upstream of or within regulation of myotube differentiation IMP
IMP: Inferred from mutant phenotype
19319192 MGI
acts upstream of or within regulation of skeletal muscle fiber development IMP
IMP: Inferred from mutant phenotype
19319192 MGI
acts upstream of ubiquitin-dependent protein catabolic process IMP
IMP: Inferred from mutant phenotype
19319192 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
19319192 MGI
located in nucleus IDA
IDA: Inferred from direct assay
19319192 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

F-box only protein 22

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (12)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-163807 22-SLF Degrader 95.72% Unkown
HY-173351 G-6599 Degrader 98.30% Unkown
HY-161794A SP3N hydrochloride Degrader 99.84% Unkown
HY-161796 UNC8732 Degrader / Unkown
HY-RS04799 FBXO22 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-161794 SP3N Degrader / Unkown
HY-178321 UNC10088 Degrader / Unkown
HY-175756 SMARCA2/4 degrader-1 Degrader / Unkown
HY-184179 TEAD degrader-1 Degrader / Unkown
HY-184968 PROTAC NSD2 degrader-1 Degrader / Unkown
HY-RS20155 Fbxo22 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26659 Fbxo22 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fbxo22 NCBI NCBI:26263