Wnk2 - WNK lysine deficient protein kinase 2 Gene

Also Known as ESTM15; mKIAA1760; 1810073P09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 75607

Summary

Predicted to enable Chloride Channel Inhibitor activity; Potassium Channel Inhibitor activity; and protein serine/threonine kinase activity. Involved in protein phosphorylation. Predicted to be located in plasma membrane. Predicted to be active in cytosol. Is expressed in central nervous system and neural retina. Orthologous to human WNK2 (WNK lysine deficient protein kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Wnk2 Products (3)

mRNA Protein Name
NM_001290311.1 NP_001277240.1 serine/threonine-protein kinase WNK2 isoform a
NM_001290313.1 NP_001277242.1 serine/threonine-protein kinase WNK2 isoform b
NM_029361.4 NP_083637.2 serine/threonine-protein kinase WNK2 isoform c

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
21733846 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein kinase WNK2

  • protein kinase lysine-deficient 2

  • protein kinase with no lysine 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-100626 WNK463 Inhibitor 99.75% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Wnk2 NCBI NCBI:65268