Upp2 - uridine phosphorylase 2 Gene

Also Known as UP2; UPASE2; UDRPASE2; 1700124F02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 76654

Summary

Enables uridine Phosphorylase activity. Involved in CMP catabolic process; UMP catabolic process; and uridine catabolic process. Located in cytosol. Is expressed in adrenal gland and gland. Orthologous to human UPP2 (uridine Phosphorylase 2). [provided by Alliance of Genome Resources, Apr 2022]

Upp2 Products (3)

mRNA Protein Name
NM_001289659.1 NP_001276588.1 uridine phosphorylase 2 isoform 1
NM_001289660.1 NP_001276589.1 uridine phosphorylase 2 isoform 2
NM_029692.3 NP_083968.1 uridine phosphorylase 2 isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables uridine phosphorylase activity IDA
IDA: Inferred from direct assay
14715930 MGI
Biological Process GO Annotation Evidence References Source
involved in CMP catabolic process IDA
IDA: Inferred from direct assay
14715930 MGI
involved in UMP catabolic process IDA
IDA: Inferred from direct assay
14715930 MGI
involved in uridine catabolic process IDA
IDA: Inferred from direct assay
14715930 MGI
Cellular Component GO Annotation Evidence References Source
is active in cytosol IDA
IDA: Inferred from direct assay
14715930 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

uridine phosphorylase 2

  • L-UrdPase

  • liver-specific uridine phosphorylase

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-106406 Benzylacyclouridine 98.02% Phase 4

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15491 UPP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21452 Upp2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27970 Upp2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Upp2 NCBI NCBI:151531