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ZNF236 - zinc finger protein 236 Gene

Also Known as ZNF236A; ZNF236B

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 7776

About ZNF236

Cytogenetic location: 18q23 Genomic coordinates (GRCh38): 18:76,822,557-76,972,901 (from NCBI)

This gene has 9 transcripts (splice variants) and 214 orthologues. Broad expression in testis (RPKM 5.8), ovary (RPKM 2.3) and 24 other tissues.

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cellular response to glucose stimulus. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ZNF236 Products (2)

mRNA	Protein	Name
NM_001306089.2	NP_001293018.1	zinc finger protein 236 isoform 1
NM_007345.4	NP_031371.3	zinc finger protein 236 isoform 2

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in cellular response to glucose stimulus	IEP IEP: Inferred from expression pattern	9299475	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF236 Protein Structure

zf-H2C2_2

zf-C2H2

zf-H2C2_2

zf-C2H2_4

zf-H2C2_2

zf-C2H2

zf-H2C2_2

0
300
600
900
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1500
1845 a.a.

Protein Preferred Names	Protein Names
zinc finger protein 236	regulated by glucose

Related Diseases

Diseases	Alias
Chromosome 18q Deletion Syndrome	18q- Syndrome Monosomy 18q Deletion Of Long Arm Of Chromosome 18 Chromosome 18q- Syndrome Deletion 18q 18q Deletion Syndrome Distal 18q Deletion Syndrome Chromosome 18 Long Arm Deletion Syndrome Chromosome 18q Monosomy Del Syndrome Chromosome 18 Deletion Syndrome
Hypothyroidism, Thyroidal Or Athyroidal, With Spiky Hair And Cleft Palate	Bamforth-Lazarus Syndrome Bamforth Syndrome Hypothyroidism, Athyroidal, With Spiky Hair And Cleft Palate Hypothyroidism Cleft Palate Hypothyroidism, Athyroidal, With Spiky Hair And Cleft Palate Athyroidal Hypothyroidism-Spiky Hair-Cleft Palate Syndrome Hypothyroidism-Cleft Palate Syndrome BLS Athyroidal Hypothyroidism With Spiky Hair And Cleft Palate
Childhood Disintegrative Disease	Childhood Disintegrative Disorder Disintegrative Psychosis Heller'S Syndrome Symbiotic Psychosis Dementia Infantilis Heller Syndrome Shared Paranoid Disorder
Cleft Palate, Isolated	Cleft Palate Isolated Cleft Palate CPI Cp Palatoschisis Cleft Palate Isolated Uranostaphyloschisis Congenital Fissure Of Palate Cleft Of Secondary Palate
Van Der Woude Syndrome	Lip-Pit Syndrome Vws Cleft Lip And/Or Palate With Mucous Cysts Of Lower Lip Vdws Lps Lip Pit Syndrome Cleft Lip/Palate With Mucous Cysts Of Lower Lip Myopathy, Actin, Congenital, With Excess Of Thin Myofilaments

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16113	ZNF236 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	ZNF236	MGD	MGI:1926950
Bos taurus	ZNF236	VGNC	VGNC:37231
Macaca mulatta	ZNF236	VGNC	VGNC:78879
Canis familiaris	ZNF236	VGNC	VGNC:48678
Rattus norvegicus	ZNF236	RGD	RGD:1309670
Felis catus	ZNF236	VGNC	VGNC:67280
Others	ZNF236	NCBI