Ulbp1 - UL16 binding protein 1 Gene
Also Known as MULT1; A430108B07Rik
Species: Mus musculus
Summary
Enables natural killer cell lectin-like receptor binding activity. Acts upstream of or within several processes, including positive regulation of immune response; positive regulation of interferon-gamma production; and positive regulation of leukocyte activation. Located in external side of plasma membrane. Is integral component of plasma membrane. Orthologous to several human genes including ULBP1 (UL16 binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Ulbp1 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_029975.2 | NP_084251.1 | NKG2D ligand 1 precursor |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables natural killer cell lectin-like receptor binding |
IPI
IPI: Inferred from physical interaction
|
12645935 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within positive regulation of immune response to tumor cell |
IDA
IDA: Inferred from direct assay
|
12645935 | MGI |
| acts upstream of or within positive regulation of macrophage activation |
IDA
IDA: Inferred from direct assay
|
12645935 | MGI |
| acts upstream of or within positive regulation of natural killer cell activation |
IDA
IDA: Inferred from direct assay
|
12645935 | MGI |
| acts upstream of or within positive regulation of nitric oxide biosynthetic process |
IDA
IDA: Inferred from direct assay
|
12645935 | MGI |
| acts upstream of or within positive regulation of type II interferon production |
IDA
IDA: Inferred from direct assay
|
12645935 | MGI |
| acts upstream of or within susceptibility to natural killer cell mediated cytotoxicity |
IDA
IDA: Inferred from direct assay
|
12645935 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in external side of plasma membrane |
IDA
IDA: Inferred from direct assay
|
12645935 | MGI |
| located in plasma membrane |
IDA
IDA: Inferred from direct assay
|
12645935 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
NKG2D ligand 1 |
|
Recombinant Ulbp1 Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P71415 | ULBP1/RAET1I Protein, Mouse (HEK293, His) | Q8HWA3 (P26-T211) | ≥ 90%, as determined by reducing SDS-PAGE. |