Epha5 - EPH receptor A5 Gene

Also Known as Els1; EHK-1; Els1.

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 79208

Summary

Enables Ephrin Receptor activity and growth factor binding activity. Involved in several processes, including cAMP-mediated signaling; dendritic spine morphogenesis; and Ephrin Receptor signaling pathway. Acts upstream of or within negative regulation of cell adhesion. Located in axon and plasma membrane. Orthologous to human EphA5 (EPH receptor A5). [provided by Alliance of Genome Resources, Apr 2022]

Epha5 Products (2)

mRNA Protein Name
NM_001169137.3 NP_001162608.1 ephrin type-A receptor 5 isoform 1 precursor
NM_024367.2 NP_077343.1 ephrin type-A receptor 5 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ephrin receptor activity IDA
IDA: Inferred from direct assay
20824214 RGD
enables growth factor binding IPI
IPI: Inferred from physical interaction
22568954 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
20824214 RGD
Biological Process GO Annotation Evidence References Source
involved in cAMP-mediated signaling IDA
IDA: Inferred from direct assay
20824214 RGD
involved in dendritic spine morphogenesis IDA
IDA: Inferred from direct assay
20824214 RGD
involved in ephrin receptor signaling pathway IDA
IDA: Inferred from direct assay
20824214 RGD
acts upstream of or within negative regulation of cell adhesion IDA
IDA: Inferred from direct assay
23242526 RGD
involved in positive regulation of CREB transcription factor activity IMP
IMP: Inferred from mutant phenotype
20824214 RGD
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
7748564 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
7748564 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ephrin type-A receptor 5

  • EPH homology kinase 1

  • eck-like sequence 1

  • tyrosine-protein kinase receptor EHK-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04429 EPHA5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-146375 UniPR505 Antagonist 99.68% Unkown
HY-10654 EphB4-IN-2 Inhibitor / Unkown
HY-RS18661 Epha5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25147 Epha5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992403 MBRC-101 Antibody Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Epha5 NCBI NCBI:2044