Abi1 - abl-interactor 1 Gene

Also Known as E3b1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 79249

Summary

Predicted to enable SH3 domain binding activity; protein tyrosine kinase activator activity; and signaling adaptor activity. Involved in postsynapse to nucleus signaling pathway. Is active in glutamatergic synapse and postsynaptic density. Orthologous to human ABI1 (abl interactor 1). [provided by Alliance of Genome Resources, Apr 2022]

Abi1 Products (1)

mRNA Protein Name
NM_024397.2 NP_077373.2 abl interactor 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17304222 RGD
Biological Process GO Annotation Evidence References Source
involved in postsynapse to nucleus signaling pathway EXP
EXP: Inferred from Experiment
17304222 RGD
involved in postsynapse to nucleus signaling pathway IDA
IDA: Inferred from direct assay
17304222 RGD
involved in postsynapse to nucleus signaling pathway IEP
IEP: Inferred from expression pattern
17304222 RGD
involved in postsynapse to nucleus signaling pathway IMP
IMP: Inferred from mutant phenotype
17304222 RGD
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse EXP
EXP: Inferred from Experiment
17304222 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
17304222 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
17304222 RGD
is active in postsynaptic density IDA
IDA: Inferred from direct assay
17304222 RGD
is active in postsynaptic density IMP
IMP: Inferred from mutant phenotype
25293574 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

abl interactor 1

  • abelson interactor 1

  • abi-1

  • eps8 SH3 domain-binding protein

  • eps8 binding protein (e3B1), alternatively spliced

  • eps8-binding protein

Abi1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Abi1 Q9QZM5 Shank3 Rattus norvegicus Q9JLU4
Y2H
17304222
Intra
Abi1 Q9QZM5 Shank3 Rattus norvegicus Q9JLU4
Pull Down
17304222
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00098 ABI1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19872 Abi1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26371 Abi1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Abi1 NCBI NCBI:10006