C11orf80 - chromosome 11 open reading frame 80 Gene

Also Known as HYDM4; TOP6BL; TOPOVIBL

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79703

About C11orf80

Cytogenetic location: 11q13.2 Genomic coordinates (GRCh38): 11:66,744,736-66,843,516 (from NCBI)

This gene has 19 transcripts (splice variants), 128 orthologues and is associated with 2 phenotypes. Broad expression in skin (RPKM 13.7), testis (RPKM 6.8) and 22 other tissues.

Summary

Predicted to be involved in meiotic DNA double-strand break formation and reciprocal meiotic recombination. Predicted to be located in chromosome. Implicated in gestational trophoblastic neoplasm. [provided by Alliance of Genome Resources, Apr 2022]

C11orf80 Products (2)

mRNA Protein Name
NM_001302084.2 NP_001289013.1 type 2 DNA topoisomerase 6 subunit B-like isoform b
NM_024650.3 NP_078926.3 type 2 DNA topoisomerase 6 subunit B-like isoform a

C11orf80 Protein Structure

DUF4554

DUF4554: Domain of unknown function (DUF4554) (171 - 298)

  • 0
  • 100
  • 200
  • 298 a.a.
Protein Preferred Names Protein Names

type 2 DNA topoisomerase 6 subunit B-like

  • type 2 DNA topoisomerase VI subunit B-like

Related Diseases

Diseases Alias
Hydatidiform Mole, Recurrent, 4

  • HYDM4
Hydatidiform Mole, Recurrent, 1

  • Hydatidiform Mole

  • Gestational Trophoblastic Disease

  • Complete Hydatidiform Mole

  • Hydm

  • HYDM1

  • Chm

  • Molar Pregnancy

  • Hydatidiform Mole, Complete

  • Hydatid Mole

  • Complete Molar Pregnancy

  • Mole, Hydatidiform, Recurrent, Type 1

  • Gestational Trophoblastic Neoplasms

  • Hydatidiform Mole, Recurrent, 2

  • Classical Hydatidiform Mole
Trophoblastic Neoplasm

  • Trophoblastic Tumor

  • Trophoblastic Neoplasms
Gestational Trophoblastic Neoplasm

  • Hydatidiform Mole

  • Molar Pregnancy

  • Gestational Trophoblastic Neoplasia

  • Gestational Trophoblastic Tumor

  • Gtn

  • Gestational Trophoblastic Disease

  • Gestational Trophoblastic Neoplasms

  • Hydatidiform Mole, Recurrent, 1

  • Hydatidiform Mole Benign

  • Trophoblastic Disease

  • Trophoblastic Disease Nos

  • Trophoblastic Disorder

  • Vesicular Mole Nos

  • Vesicular Mole

  • Hydatidiform Mole Nos
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01693 C11orf80 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus C11orf80 MGD MGI:2685806
Canis familiaris C11orf80 VGNC VGNC:59051
Rattus norvegicus C11orf80 RGD RGD:1563323
Macaca mulatta C11orf80 VGNC VGNC:100894
Felis catus C11orf80 VGNC VGNC:60593
Others C11orf80 NCBI