NPEPL1 - aminopeptidase like 1 Gene

Also Known as bA261P9.2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79716

About NPEPL1

This gene has 9 transcripts (splice variants), 205 orthologues and 1 paralogue. Ubiquitous expression in fat (RPKM 17.5), spleen (RPKM 15.8) and 25 other tissues.

Summary

Predicted to enable manganese ion binding activity and metalloaminopeptidase activity. Predicted to be involved in proteolysis. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

NPEPL1 Products (3)

mRNA Protein Name
NM_001204872.2 NP_001191801.1 probable aminopeptidase NPEPL1 isoform 2
NM_001204873.2 NP_001191802.1 probable aminopeptidase NPEPL1 isoform 3
NM_024663.4 NP_078939.3 probable aminopeptidase NPEPL1 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NPEPL1 Protein Structure

Peptidase_M17

Peptidase_M17: Cytosol aminopeptidase family, catalytic domain (178 - 483)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 523 a.a.
Protein Preferred Names Protein Names

probable aminopeptidase NPEPL1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09478 NPEPL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19797 Npepl1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26293 Npepl1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus NPEPL1 RGD RGD:1311351
Felis catus NPEPL1 VGNC VGNC:63867
Bos taurus NPEPL1 VGNC VGNC:32197
Canis familiaris NPEPL1 VGNC VGNC:43916
Mus musculus NPEPL1 MGD MGI:2448523
Others NPEPL1 NCBI