Rab27b - RAB27B, member RAS oncogene family Gene

Also Known as 2310021G14Rik; B130064M09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 80718

Summary

Enables GTP binding activity and GTPase activity. Predicted to be involved in several processes, including anterograde axonal protein transport; melanosome transport; and synaptic vesicle endocytosis. Located in Golgi apparatus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study platelet storage pool deficiency. Orthologous to human RAB27B (RAB27B, member Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Rab27b Products (4)

mRNA Protein Name
NM_001082553.2 NP_001076022.1 ras-related protein Rab-27B isoform 1
NM_001302798.1 NP_001289727.1 ras-related protein Rab-27B isoform 1
NM_001302799.1 NP_001289728.1 ras-related protein Rab-27B isoform 2
NM_030554.4 NP_085031.3 ras-related protein Rab-27B isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTP binding IDA
IDA: Inferred from direct assay
18940604 MGI
enables GTPase activity IDA
IDA: Inferred from direct assay
18940604 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16716193 MGI
Cellular Component GO Annotation Evidence References Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
14724135 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-related protein Rab-27B

Rab27b Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Rab27b Q99P58 Mlph Mus musculus Q91V27
X-Ray Diffraction
18940604
Intra
Rab27b Q99P58 Mlph Mus musculus Q91V27
GMS
18940604
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11538 RAB27B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-184152 IMP-2552 Inhibitor / Unkown
HY-184153 IMP-2958 / Unkown
HY-RS21183 Rab27b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27699 Rab27b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rab27b NCBI NCBI:5874