Ifitm2 - interferon induced transmembrane protein 2 Gene

Also Known as mil-3; DSPA2c; Ifitm3l; fragilis3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 80876

Summary

Involved in negative regulation of viral entry into host cell and response to virus. Acts upstream of or within defense response to virus. Predicted to be located in late endosome membrane and lysosomal membrane. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane. Is expressed in several structures, including 4-cell stage embryo; brain; genitourinary system; hemolymphoid system; and liver. Orthologous to human IFITM2 (interferon induced transmembrane protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Ifitm2 Products (1)

mRNA Protein Name
NM_030694.1 NP_109619.1 interferon-induced transmembrane protein 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within defense response to virus IDA
IDA: Inferred from direct assay
20064371 MGI
involved in negative regulation of viral entry into host cell IDA
IDA: Inferred from direct assay
21253575 MGI
involved in response to virus IDA
IDA: Inferred from direct assay
21253575 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interferon-induced transmembrane protein 2

  • dispanin subfamily A member 2c

  • fragilis R

  • fragilis protein 3

  • interferon induced transmembrane protein, like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06567 IFITM2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21869 Ifitm2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992379 IB001 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ifitm2 NCBI NCBI:10581