Cib1 - calcium and integrin binding 1 Gene

Also Known as Cib; Sip2-28

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 81823

Summary

Enables protein C-terminus binding activity and protein kinase binding activity. Involved in positive regulation of calcineurin-NFAT signaling cascade. Located in several cellular components, including axon; dendrite; and neuronal cell body. Biomarker of Alzheimer's disease. Human ortholog(s) of this gene implicated in epidermodysplasia verruciformis. Orthologous to human CIB1 (calcium and Integrin binding 1). [provided by Alliance of Genome Resources, Apr 2022]

Cib1 Products (1)

mRNA Protein Name
NM_031145.2 NP_112407.1 calcium and integrin-binding protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10523297 RGD
enables protein kinase binding IPI
IPI: Inferred from physical interaction
10523297 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of calcineurin-NFAT signaling cascade IMP
IMP: Inferred from mutant phenotype
20639889 RGD
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
16257512 RGD
located in dendrite IDA
IDA: Inferred from direct assay
10523297 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
10523297 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calcium and integrin-binding protein 1

  • DNA-PKcs-interacting protein

  • KIP

  • calcium- and integrin-binding protein

  • calmyrin

  • kinase-interacting protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-162558 NCGC00351170 Inhibitor 99.05% Unkown
HY-RS02706 CIB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19584 Cib1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26081 Cib1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cib1 NCBI NCBI:10519