Ucn3 - urocortin 3 Gene

Also Known as ucn III

Species: Mus musculus

Gene Type: protein coding
Gene ID: 83428

Summary

This gene encodes a member of the corticotropin-releasing hormone peptide family that participates in coordinating autonomic, endocrine, and behavioral responses to stress. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional hormone. The pancreatic islets isolated from mice lacking the encoded protein secrete less Insulin in response to high glucose concentrations. Transgenic mice overexpressing the encoded protein exhibit a metabolically favorable phenotype resisting obesity and hyperglycemia on a high-fat diet. [provided by RefSeq, Sep 2016]

Ucn3 Products (1)

mRNA Protein Name
NM_031250.5 NP_112540.2 urocortin-3 preproprotein

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11416224 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
11416224 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

urocortin-3

  • Urocortin III

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P1858A Urocortin III, mouse TFA Activator 98.06% Unkown
HY-P1858 Urocortin III, mouse Activator 98.29% Unkown
HY-RS15409 UCN3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21451 Ucn3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27969 Ucn3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ucn3 NCBI NCBI:114131