RXRG - retinoid X receptor gamma Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 83574

About RXRG

Primary_assembly 13: 79,743,563-79,785,167 forward strand.mRatBN7.2:CM026986.1

This gene has 2 transcripts (splice variants), 277 orthologues, 11 paralogues and is associated with 5 phenotypes. Biased expression in Heart (RPKM 248.), Muscle (RPKM 23.6) and 5 other tissues.

Summary

Predicted to enable identical protein binding activity; nuclear receptor activity; and retinoic acid-responsive element binding activity. Involved in several processes, including nervous system development; regulation of myelination; and response to retinoic acid. Located in nucleus. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human RXRG (retinoid X receptor gamma). [provided by Alliance of Genome Resources, Apr 2022]

RXRG Products (1)

mRNA Protein Name
NM_031765.1 NP_113953.1 retinoic acid receptor RXR-gamma

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular response to hormone stimulus IEP
IEP: Inferred from expression pattern
10328854 RGD
involved in heart development IEP
IEP: Inferred from expression pattern
10328854 RGD
involved in neuron differentiation IEP
IEP: Inferred from expression pattern
15664689 RGD
involved in peripheral nervous system development IEP
IEP: Inferred from expression pattern
9682978 RGD
involved in regulation of myelination IDA
IDA: Inferred from direct assay
20648638 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
18923996 RGD
involved in response to retinoic acid IEP
IEP: Inferred from expression pattern
17161848 RGD
involved in skeletal muscle tissue development IEP
IEP: Inferred from expression pattern
9389449 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RXRG Protein Structure

Nuc_recep-AF1

Nuc_recep-AF1: pfam11825 (24 - 133)

NR_DBD_RXR

NR_DBD_RXR: cd06956 (136 - 212)

NR_LBD_RXR_like

NR_LBD_RXR_like: cd06943 (232 - 441)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 464 a.a.
Protein Preferred Names Protein Names

retinoic acid receptor RXR-gamma

  • RXR gamma-1

  • nuclear receptor subfamily 2 group B member 3

  • retinoic X receptor gamma-1

  • retinoic acid receptor RXR-gamma-like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12364 Rxrg Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12365 RXRG Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12363 RXRG Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-160212 JP3000 Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens RXRG NCBI NCBI:6258