Gmeb2 - glucocorticoid modulatory element binding protein 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 83635

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Orthologous to human GMEB2 (glucocorticoid modulatory element binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Gmeb2 Products (2)

mRNA Protein Name
NM_001389211.1 NP_001376140.1 glucocorticoid modulatory element-binding protein 2 isoform 2
NM_031803.2 NP_113991.2 glucocorticoid modulatory element-binding protein 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
10894151 RGD
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
14705952 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
10894151 RGD
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
10894151 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
10894151 RGD
involved in regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
14705952 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glucocorticoid modulatory element-binding protein 2

  • GMEB-2

Gmeb2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Gmeb2 O88873 GMEB1 Homo sapiens Q9Y692-2
Anti Tag CoIP
10894151
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05517 GMEB2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21584 Gmeb2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28102 Gmeb2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gmeb2 NCBI NCBI:26205