Nsfl1c - NSFL1 cofactor Gene

Also Known as p47; XY40

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 83809

Summary

Enables ATPase binding activity and ubiquitin binding activity. Contributes to phospholipid binding activity. Involved in Golgi organization and membrane fusion. Located in cytosol and spindle pole centrosome. Part of VCP-NSFL1C complex. Orthologous to human NSFL1C (NSFL1 cofactor). [provided by Alliance of Genome Resources, Apr 2022]

Nsfl1c Products (1)

mRNA Protein Name
NM_031981.2 NP_114187.1 NSFL1 cofactor p47

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ATPase binding IPI
IPI: Inferred from physical interaction
12146947 RGD
contributes to phospholipid binding IDA
IDA: Inferred from direct assay
12146947 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
9214505 RGD
enables ubiquitin binding IDA
IDA: Inferred from direct assay
18775313 RGD
Biological Process GO Annotation Evidence References Source
involved in Golgi organization IDA
IDA: Inferred from direct assay
12146947 RGD
involved in membrane fusion IDA
IDA: Inferred from direct assay
12146947 RGD
Cellular Component GO Annotation Evidence References Source
part of VCP-NSFL1C complex IPI
IPI: Inferred from physical interaction
9214505 RGD
located in cytosol IDA
IDA: Inferred from direct assay
9214505 RGD
located in spindle pole centrosome IDA
IDA: Inferred from direct assay
23649807 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NSFL1 cofactor p47

  • NSFL1 (p97) cofactor (p47)

  • XY body-associated protein XY40

  • p97 cofactor p47

Nsfl1c Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Nsfl1c O35987 Vcp Rattus norvegicus P46462
GMS
16601695
Intra
Nsfl1c O35987 Vcp Rattus norvegicus P46462
Pull Down
20691684
Intra
Nsfl1c O35987 Vcp Rattus norvegicus P46462
EM
16601695
Intra
Nsfl1c O35987 Vcp Rattus norvegicus P46462
Anti Tag CoIP
9214505
Intra
Nsfl1c O35987 Vcp Rattus norvegicus P46462
Anti Bait CoIP
10811609
Intra
Nsfl1c O35987 Vcp Rattus norvegicus P46462
ITC
16601695
Intra
Nsfl1c O35987 Vcp Rattus norvegicus P46462
GMS
9214505
Cross
Nsfl1c O35987 Vcp Mus musculus Q01853
Competition Binding
10811609
Cross
Nsfl1c O35987 Vcp Mus musculus Q01853
Pull Down
20691684
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09592 NSFL1C Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nsfl1c NCBI NCBI:55968