KLF16 - KLF transcription factor 16 Gene

Also Known as DRRF; BTEB4; NSLP2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 83855

About KLF16

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:1,852,399-1,876,536 (from NCBI)

This gene has 4 transcripts (splice variants), 234 orthologues and 22 paralogues. Ubiquitous expression in brain (RPKM 6.7), colon (RPKM 5.5) and 25 other tissues.

Summary

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within Dopamine Receptor signaling pathway. Predicted to be located in nucleus. Predicted to be part of chromatin. [provided by Alliance of Genome Resources, Apr 2022]

KLF16 Products (1)

mRNA Protein Name
NM_031918.4 NP_114124.1 Krueppel-like factor 16

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

KLF16 Protein Structure

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (143 - 169)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (174 - 198)

  • 0
  • 100
  • 200
  • 252 a.a.
Protein Preferred Names Protein Names

Krueppel-like factor 16

  • BTE-binding protein 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07337 KLF16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21582 Glis2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21618 Klf16 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28136 Klf16 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus KLF16 RGD RGD:1305966
Felis catus KLF16 VGNC VGNC:102625
Mus musculus KLF16 MGD MGI:2153049
Canis familiaris KLF16 VGNC VGNC:108247
Bos taurus KLF16 VGNC VGNC:58603
Others KLF16 NCBI