MCHR2 - melanin concentrating hormone receptor 2 Gene

Also Known as SLT; MCH2; MCH2R; GPR145; GPRv17; MCH-2R; MCH-R2; MCHR-2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84539

About MCHR2

Cytogenetic location: 6q16.2 Genomic coordinates (GRCh38): 6:99,918,519-99,994,223 (from NCBI)

This gene has 2 transcripts (splice variants), 111 orthologues and 33 paralogues. Biased expression in brain (RPKM 3.0) and testis (RPKM 2.4).

Summary

Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

MCHR2 Products (2)

mRNA Protein Name
NM_001040179.2 NP_001035269.1 melanin-concentrating hormone receptor 2
NM_032503.3 NP_115892.2 melanin-concentrating hormone receptor 2

MCHR2 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (51 - 306)

  • 0
  • 100
  • 200
  • 300
  • 340 a.a.
Protein Preferred Names Protein Names

melanin-concentrating hormone receptor 2

  • G protein-coupled receptor slt

Related Diseases

Diseases Alias
Schizophrenia 4

  • SCZD4

  • Schizophrenia, Susceptibility To, 4

  • Schizophrenia Susceptibility Locus, Chromosome 22q11-Related

  • Schizophrenia Susceptibility Locus Chromosome 22-Related

  • Schizophrenia, Type 4
Griscelli Syndrome, Type 3

  • Griscelli Syndrome Type 3

  • GS3

  • Griscelli-Prunieras Syndrome Type 3

  • Hypomelanosis With No Immunologic Or Neurologic Manifestations

  • Griscelli Syndrome 3
Localized Chondrosarcoma
Body Mass Index Quantitative Trait Locus 11

  • OBESITY

  • Obesity, Susceptibility To

  • Leanness, Inherited

  • Obesity, Susceptibility To, Bmiq11

  • Obesity, Mild, Early-Onset

  • Obesity, Association With

  • Obesity, Early-Onset, Susceptibility To

  • Obesity, Severe

  • Obesity, Severe, And Type Ii Diabetes

  • Obesity, Late-Onset

  • Obesity , Susceptibility To

  • BMIQ11

  • Obesity Bmiq11

  • Obesity, Early-Onset

  • Simple Obesity Nos

  • Excess Fat

  • Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified

  • Adiposis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P1205A MCH(human, mouse, rat) TFA Ligand 99.09% Unkown
HY-P1525A Melanin Concentrating Hormone, salmon TFA Agonist 99.91% Unkown
HY-P1525 Melanin Concentrating Hormone, salmon Agonist 99.09% Unkown
HY-P1204 [Ala17]-MCH Agonist 98.28% Unkown
HY-107626 ATC0065 Antagonist 99.09% Unkown
HY-107626A ATC0065 free base Antagonist / Unkown
HY-P1204A [Ala17]-MCH TFA Agonist / Unkown
HY-RS08228 MCHR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown