Sos2 - SOS Ras/Rho guanine nucleotide exchange factor 2 Gene

Also Known as Sos1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 85384

Summary

Predicted to enable guanyl-nucleotide exchange factor activity. Involved in positive regulation of small GTPase mediated signal transduction. Human ortholog(s) of this gene implicated in Noonan syndrome 9. Orthologous to human SOS2 (SOS Ras/Rho guanine nucleotide exchange factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Sos2 Products (1)

mRNA Protein Name
NM_001135561.1 NP_001129033.1 son of sevenless homolog 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in positive regulation of small GTPase mediated signal transduction IMP
IMP: Inferred from mutant phenotype
20219970 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

son of sevenless homolog 2

  • son of sevenless 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-145737A PROTAC SOS1 degrader-1 TFA 98.38% Unkown
HY-145737 PROTAC SOS1 degrader-1 / Unkown
HY-161173 PROTAC SOS1 degrader-5 / Unkown
HY-168480 SOS2 ligand 1 Ligand / Unkown
HY-184855 (S,S,S,S)-AHPC-Me / Unkown
HY-RS13577 SOS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19958 Sos2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26460 Sos2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sos2 NCBI NCBI:6655