GPR52 - G protein-coupled receptor 52 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9293

About GPR52

Cytogenetic location: 1q25.1 Genomic coordinates (GRCh38): 1:174,447,964-174,449,545 (from NCBI)

This gene has 1 transcript (splice variant), 88 orthologues and 25 paralogues.

Summary

Members of the G protein-coupled receptor (GPR) family play important roles in signal transduction from the external environment to the inside of the cell.[supplied by OMIM, Jul 2002]

GPR52 Products (1)

mRNA Protein Name
NM_005684.5 NP_005675.3 G-protein coupled receptor 52

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables G protein-coupled receptor activity IDA
IDA: Inferred from direct assay
24587241 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32814053 GOA
Biological Process GO Annotation Evidence References Source
involved in response to xenobiotic stimulus IDA
IDA: Inferred from direct assay
24587241 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GPR52 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (57 - 317)

  • 0
  • 100
  • 200
  • 300
  • 361 a.a.
Protein Preferred Names Protein Names

G-protein coupled receptor 52

  • probable G-protein coupled receptor 52

GPR52 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
GPR52 Q9Y2T5 ATN1 Homo sapiens Q86V38
Validated Y2H
32814053
Intra
GPR52 Q9Y2T5 ATN1 Homo sapiens Q86V38
Y2H Pooling
32814053
Intra
GPR52 Q9Y2T5 ATN1 Homo sapiens Q86V38
Y2H Array
32814053
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-101787 TP-024 99.96% Unkown
HY-145468 GPR52 antagonist-1 Antagonist 99.86% Unkown
HY-138639 PW0787 98.79% Unkown
HY-154980 NXE0041178 Agonist 99.97% Unkown
HY-147395 GPR52 agonist-1 Agonist 99.21% Unkown
HY-163671 PW0729 Agonist 99.55% Unkown
HY-176900 GPR52 agonist-4 Modulator 98.09% Unkown
HY-184192 R-185 Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus GPR52 VGNC VGNC:29590
Mus musculus GPR52 MGD MGI:3643278
Rattus norvegicus GPR52 RGD RGD:1587949
Others GPR52 NCBI