Pag1 - phosphoprotein associated with glycosphingolipid microdomains 1 Gene

Also Known as Cbp; Pag; F730007C19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 94212

Summary

Predicted to enable SH2 domain binding activity. Involved in negative regulation of T cell activation. Predicted to be located in plasma membrane. Predicted to be active in membrane raft. Is expressed in several structures, including brain and spinal cord. Orthologous to human PAG1 (phosphoprotein membrane anchor with glycosphingolipid microdomains 1). [provided by Alliance of Genome Resources, Apr 2022]

Pag1 Products (2)

mRNA Protein Name
NM_001195031.1 NP_001181960.1 phosphoprotein associated with glycosphingolipid-enriched microdomains 1
NM_053182.5 NP_444412.2 phosphoprotein associated with glycosphingolipid-enriched microdomains 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12612075 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of T cell activation IDA
IDA: Inferred from direct assay
12612075 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphoprotein associated with glycosphingolipid-enriched microdomains 1

  • Csk-binding protein

  • phosphoprotein transmembrane adaptor 1

  • phosphoprotein-associated with GEMs

  • transmembrane phosphoprotein Cbp

Pag1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Pag1 Q3U1F9 Csk Mus musculus P41241
Affinity Chrom
26512138
Intra
Pag1 Q3U1F9 Csk Mus musculus P41241
Anti Bait CoIP
26512138
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09971 PAG1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17709 Pappa Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18364 Pag1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24843 Pag1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pag1 NCBI NCBI:55824