2. Gene
  3. CDYL - chromodomain Y like Gene

CDYL - chromodomain Y like Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CDYL1

Gene ID: 9425 | Gene type: protein coding

About CDYL

Cytogenetic location: 6p25.1 Genomic coordinates (GRCh38): 6:4,706,138-4,955,544 (from NCBI)

This gene has 9 transcripts (splice variants), 215 orthologues and 13 paralogues. Ubiquitous expression in placenta (RPKM 8.5), endometrium (RPKM 8.1) and 25 other tissues.

Summary

Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]

CDYL Products(6)

mRNA Protein Name
NM_001143970.2 NP_001137442.1 chromodomain Y-like protein isoform d
NM_001143971.2 NP_001137443.1 chromodomain Y-like protein isoform d
NM_001368125.1 NP_001355054.1 chromodomain Y-like protein isoform e
NM_001368126.1 NP_001355055.1 chromodomain Y-like protein isoform f
NM_001368127.1 NP_001355056.1 chromodomain Y-like protein isoform g
NM_004824.4 NP_004815.3 chromodomain Y-like protein isoform a

CDYL Protein Structure

Chromo

Chromo: Chromo (CHRromatin Organisation MOdifier) domain (62 - 112)

ECH_1

ECH_1: Enoyl-CoA hydratase/isomerase (348 - 591)

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  • 598 a.a.
Protein Preferred Names Protein Names

chromodomain Y-like protein

CDY-like, autosomal

Related Diseases

Diseases Alias
Chromosome 6pter-P24 Deletion Syndrome

6p Subtelomeric Deletion Syndrome

6p25 Microdeletion Syndrome

Distal Monosomy 6p

Distal Deletion 6p

Monosomy 6p25
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02433 CDYL Human Pre-designed siRNA Set A / Unkown
HY-RS02434 CDYL2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CDYL RGD RGD:1549745
Felis catus CDYL VGNC VGNC:102399
Macaca mulatta CDYL VGNC VGNC:70998
Mus musculus CDYL MGD MGI:1339956
Bos taurus CDYL VGNC VGNC:55900
Canis familiaris CDYL VGNC VGNC:59137