GREB1 - growth regulating estrogen receptor binding 1 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9687

About GREB1

Cytogenetic location: 2p25.1 Genomic coordinates (GRCh38): 2:11,482,888-11,642,788 (from NCBI)

This gene has 10 transcripts (splice variants), 202 orthologues and 1 paralogue. Biased expression in ovary (RPKM 38.8), prostate (RPKM 13.2) and 2 other tissues.

Summary

This gene is an estrogen-responsive gene that is an early response gene in the estrogen receptor-regulated pathway. It is thought to play an important role in hormone-responsive tissues and Cancer. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

GREB1 Products (3)

mRNA Protein Name
NM_014668.4 NP_055483.2 protein GREB1 isoform a
NM_033090.3 NP_149081.1 protein GREB1 isoform b
NM_148903.3 NP_683701.2 protein GREB1 isoform c
Protein Preferred Names Protein Names

protein GREB1

  • gene regulated by estrogen in breast cancer

Related Diseases

Diseases Alias
Mayer-Rokitansky-Kuster-Hauser Syndrome

  • Mrkh Syndrome

  • Rokitansky Syndrome

  • Mullerian Aplasia

  • Mrkh Anomaly

  • Congenital Absence Of Uterus And Vagina

  • Congenital Absence Of The Uterus And Vagina

  • Genital Renal Ear Syndrome

  • Mayer-Rokitansky-Küster-Hauser Syndrome

  • Mullerian Dysgenesis

  • Müllerian Agenesis

  • Rokitansky Kuster Hauser Syndrome

  • MRKH

  • Mullerian Aplasia/Dysgenesis

  • Von Mayer-Rokitansky-Kuster Anomaly

  • Mrk Anomaly

  • Uterus Bipartitus Solidus Rudimentarius Cum Vagina Solida

  • Cauv

  • Mullerian Agenesis

  • Aplasia Of The Mullerian Ducts

  • Mullerian Duct Failure

  • Müllerian Aplasia

  • Rokitansky-Kuster-Hauser Syndrome

  • RKH SYNDROME
Ovarian Sex-Cord Stromal Tumor

  • Ovarian Sex Cord Tumor With Annular Tubules

  • Ovarian Sex Cord-Stromal Tumor

  • Stromal Tumor Of Ovary
Breast Cancer

  • Breast Carcinoma

  • Male Breast Cancer

  • Breast Cancer, Familial

  • Malignant Neoplasm Of Breast

  • Breast Cancer, Susceptibility To

  • Breast Cancer, Early-Onset

  • Malignant Tumor Of Breast

  • Carcinoma Of Male Breast

  • Breast Cancer, Invasive Ductal

  • Breast Cancer, Protection Against

  • Breast Cancer, Somatic

  • Breast Cancer, Male

  • Breast Cancer, Lobular, Somatic

  • Breast Tumor

  • Mammary Cancer

  • Mammary Tumor

  • Malignant Neoplasm Of Male Breast

  • Mammary Carcinoma

  • Male Breast Carcinoma

  • Familial Cancer Of Breast

  • Invasive Ductal Breast Carcinoma

  • Breast Cancer Susceptibility

  • Breast Cancer, Male, Susceptibility To

  • Breast Cancer, Early-Onset, Susceptibility To

  • Malignant Tumor Of The Breast

  • Mammary Neoplasm

  • Primary Breast Cancer

  • Neoplasm Of Male Breast

  • Carcinoma Of Breast

  • Breast Cancer In Men

  • Familial Breast Cancer

  • Cancer Of Breast

  • BC

  • Breast Cancer Familial

  • Breast Cancer Familial Male

  • Breast Cancer, Familial Male

  • Breast Male Carcinoma

  • Breast Neoplasms

  • Breast Neoplasms, Male

  • Mammary Tumors

  • Mammary Carcinomas

  • Cancer, Breast

  • Cancer, Breast, Susceptibility

  • Invasive Breast Ductal Carcinoma

  • Breast Neoplasm

  • Susceptibility To Breast Cancer

  • Mammary Neoplasms

  • Animal Mammary Neoplasms

  • Primary Malignant Neoplasm Of Breast

  • Infiltrating Ductal Carcinoma Of Breast

  • Infiltrating Duct Carcinoma Of Unspecified Site

  • Infiltrating Ductular Carcinoma Of Unspecified Site

  • Invasive Breast Carcinoma Of No Special Type

  • Microinvasive Carcinoma Of Breast

  • Carcinoma With Apocrine Differentiation
Prostate Cancer

  • Prostate Carcinoma

  • Prostate Cancer, Familial

  • Prostate Neoplasm

  • Prostate Cancer, Somatic

  • Prostate Cancer, Susceptibility To

  • Prostatic Cancer

  • Prostatic Neoplasms

  • Hereditary Prostate Cancer

  • Prostatic Neoplasm

  • Cancer Of Prostate

  • Carcinoma Of Prostate

  • Familial Prostate Cancer

  • Familial Prostate Carcinoma

  • Malignant Tumor Of Prostate

  • Malignant Neoplasm Of Prostate

  • Prostate Cancer, Familial, Susceptibility To

  • Malignant Tumor Of The Prostate

  • Ngp - New Growth Of Prostate

  • Tumor Of The Prostate

  • Prostate Cancer, Hereditary

  • Cancer Of The Prostate

  • Malignant Neoplasm Of The Prostate

  • Prostatic Carcinoma

  • PC

  • Prca

  • Cancer, Prostate

  • Malignant Prostatic Tumour

  • Malignant Tumour Of Prostate

  • Primary Prostate Cancer

  • Primary Malignant Neoplasm Of Prostate

  • Prostate Gland Cancer
Amelogenesis Imperfecta, Type Ig

  • Enamel-Renal Syndrome

  • Ers

  • Amelogenesis Imperfecta Type 1g

  • AI1G

  • Enamel-Renal-Gingival Syndrome

  • Amelogenesis Imperfecta And Gingival Fibromatosis Syndrome

  • Aigfs

  • Amelogenesis Imperfecta, Hypoplastic, With Nephrocalcinosis

  • Amelogenesis Imperfecta Hypoplastic With Nephrocalcinosis

  • Amelogenesis Imperfecta Type Ig

  • Amelogenesis Imperfecta-Nephrocalcinosis Syndrome

  • Amelogenesis Imperfecta 1g

  • Hypoplastic Amelogenesis Imperfecta With Nephrocalcinosis

  • Amelogenesis Imperfecta Nephrocalcinosis
Amelogenesis Imperfecta

  • Ai

  • Congenital Enamel Hypoplasia

  • Al - [Amelogenesis Imperfecta]
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-112611 H3B-5942 Inhibitor 98.25% Unkown
HY-179433 PROTAC AR Degrader-12 98.52% Unkown
HY-RS05782 GREB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05783 GREB1L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21588 Greb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28106 Greb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus GREB1 VGNC VGNC:53640
Rattus norvegicus GREB1 RGD RGD:1564091
Canis familiaris GREB1 VGNC VGNC:53638
Mus musculus GREB1 MGD MGI:2149712
Macaca mulatta GREB1 VGNC VGNC:73227
Felis catus GREB1 VGNC VGNC:80109
Others GREB1 NCBI