ZBTB40 - zinc finger and BTB domain containing 40 Gene

Homo sapiens

Also known as ZNF923

Gene ID: 9923 | Gene type: protein coding

About ZBTB40

Cytogenetic location: 1p36.12 Genomic coordinates (GRCh38): 1:22,428,909-22,531,154 (from NCBI)

This gene has 5 transcripts (splice variants), 179 orthologues and is associated with 1 phenotype. Ubiquitous expression in lymph node (RPKM 6.6), spleen (RPKM 6.6) and 25 other tissues.

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cellular response to DNA damage stimulus. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ZBTB40 Products(3)

mRNA	Protein	Name
NM_001083621.2	NP_001077090.1	zinc finger and BTB domain-containing protein 40 isoform a
NM_001330398.2	NP_001317327.1	zinc finger and BTB domain-containing protein 40 isoform b
NM_014870.4	NP_055685.3	zinc finger and BTB domain-containing protein 40 isoform a

ZBTB40 Protein Structure

BTB

zf-C2H2_4

zf-H2C2_2

zf-C2H2_4

zf-C2H2

zf-C2H2_4

0
200
400
600
800
1000
1239 a.a.

Protein Preferred Names

Protein Names

zinc finger and BTB domain-containing protein 40

Related Diseases

Diseases

Alias

Osteoporosis

Postmenopausal Osteoporosis	Osteoporosis, Postmenopausal
Bone Mineral Density Quantitative Trait Locus	Bmnd
Osteoporosis, Involutional	Osteoporosis, Susceptibility To
Osteoporosis, Postmenopausal, Susceptibility	Bone Mineral Density Variation Qtl, Osteoporosis
OSTEOP	Involutional Osteoporosis
Senile Osteoporosis	Osteoporosis Postmenopausal
Bone Mineral Density, Quantitative Trait Locus	Osteoporosis, Senile
Idiopathic Osteoporosis	Bone Rarefaction Nos
Type 1 Osteoporosis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15975	ZBTB40 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ZBTB40	RGD	RGD:1309866
Macaca mulatta	ZBTB40	VGNC	VGNC:79771
Canis familiaris	ZBTB40	VGNC	VGNC:48535
Bos taurus	ZBTB40	VGNC	VGNC:37079
Mus musculus	ZBTB40	MGD	MGI:2682254
Felis catus	ZBTB40	VGNC	VGNC:67170

Name
Email *

	Sorry, but the email address you supplied was invalid.