1. Neuronal Signaling
  2. Amyloid-β
  3. Glutaminyl Cyclase Inhibitor 3

Glutaminyl Cyclase Inhibitor 3 

Cat. No.: HY-101282
Handling Instructions

Glutaminyl Cyclase Inhibitor 3 (compound 212 ), a designed anti-Alzheimer’s compound, is a potent human Glutaminyl Cyclase (GC) inhibitor, with an IC50 of 4.5 nM. Glutaminyl Cyclase-IN-1 (compound 212) significantly reduced the brain concentrations of pyroform Aβ and total Aβ and restored cognitive functions.

For research use only. We do not sell to patients.

Glutaminyl Cyclase Inhibitor 3 Chemical Structure

Glutaminyl Cyclase Inhibitor 3 Chemical Structure

CAS No. : 2092921-50-9

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Description

Glutaminyl Cyclase Inhibitor 3 (compound 212 ), a designed anti-Alzheimer’s compound, is a potent human Glutaminyl Cyclase (GC) inhibitor, with an IC50 of 4.5 nM. Glutaminyl Cyclase-IN-1 (compound 212) significantly reduced the brain concentrations of pyroform Aβ and total Aβ and restored cognitive functions[1].

IC50 & Target

IC50: 4.5 nM (hGC)[1].

Molecular Weight

468.61

Formula

C₂₄H₃₂N₆O₂S

CAS No.

2092921-50-9

SMILES

COC1=C(OCCCCC2=CC(N)=NC=C2)C=CC(NC(NCCCN3C(C)=CN=C3)=S)=C1

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Glutaminyl Cyclase Inhibitor 3
Cat. No.:
HY-101282
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