GmhA-IN-1
GmhA-IN-1 (compound 17) is an inhibitor of GmhA with an IC50 value of 2.4 nM. GmhA-IN-1 enhances the activity of erythromycin and rifampicin on wild-type E. coli.
For research use only. We do not sell to patients.
- CAS No.: 1606387-54-5
- Formula: C6H14NO9P
- Molecular Weight:275.15
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | CC50 |
>1000 μM
Compound: 17
|
Cytotoxicity against human HepG2 cells incubated overnight by Celltiter aqueous one solution cell proliferation assay
Cytotoxicity against human HepG2 cells incubated overnight by Celltiter aqueous one solution cell proliferation assay
|
[PMID: 38598312] |
Chemical Information
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CAS No. 1606387-54-5
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Molecular Weight 275.15
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Formula C6H14NO9P
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SMILES
O=CN(C[C@@H]([C@@H]([C@@H](COP(O)(O)=O)O)O)O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)