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Art. -Nr.: HY-158241

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GmhA-IN-1

GmhA-IN-1 (compound 17) is an inhibitor of GmhA with an IC₅₀ value of 2.4 nM. GmhA-IN-1 enhances the activity of erythromycin and rifampicin on wild-type E. coli.

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CAS. Nr.: 1606387-54-5
Formel: C₆H₁₄NO₉P
Molecular Weight:275.15

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

GmhA-IN-1 Chemical Structure

CAS. Nr.: 1606387-54-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

GmhA-IN-1 (compound 17) is an inhibitor of GmhA with an IC₅₀ value of 2.4 nM. GmhA-IN-1 enhances the activity of erythromycin and rifampicin on wild-type E. coli^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	CC₅₀	>1000 μM Compound: 17	Cytotoxicity against human HepG2 cells incubated overnight by Celltiter aqueous one solution cell proliferation assay Cytotoxicity against human HepG2 cells incubated overnight by Celltiter aqueous one solution cell proliferation assay	[PMID: 38598312]

Chemical Information

CAS. Nr. 1606387-54-5
Molecular Weight 275.15
Formel C₆H₁₄NO₉P
SMILES

O=CN(C[C@@H]([C@@H]([C@@H](COP(O)(O)=O)O)O)O)O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. François Moreau, et al. Potentiating Activity of GmhA Inhibitors on Gram-Negative Bacteria. J Med Chem. 2024, 67, 8. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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