2. Membrane Transporter/Ion Channel
  3. HCN Channel
  4. HCN2-IN-3

HCN2-IN-3 is an orally active HCN2 inhibitor. HCN2-IN-3 inhibits the activity of HCN2 ion channels. HCN2-IN-3 is applicable to research related to pain, tinnitus, central nervous system diseases, mental illnesses and mood disorders.

For research use only. We do not sell to patients.

HCN2-IN-3

HCN2-IN-3 Chemical Structure

CAS No. : 3080808-83-6

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HCN2-IN-3 Related Antibodies

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Description

HCN2-IN-3 is an orally active HCN2 inhibitor. HCN2-IN-3 inhibits the activity of HCN2 ion channels. HCN2-IN-3 is applicable to research related to pain, tinnitus, central nervous system diseases, mental illnesses and mood disorders[1].

In Vitro

HCN2 modulator-1 (Compound 19) potently and selectively inhibits human HCN2 channels with an IC50 of 9 nM, and exhibits no significant activity against human HCN1 or HCN4 channels[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

HCN2-IN-3 Related Antibodies
Molecular Weight

459.45

Formula

C24H21N5O5
CAS No.
SMILES

N#CC1=C(C2=CN=C3C(C(NC(C4=C(C)OC=C4)=O)=NN3CC(C)OC)=C2)C=CC5=C1OCO5
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HCN2-IN-3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HCN2-IN-33080808-83-6HCN ChannelHyperpolarization activated cyclic nucleotide gated channelsHCN2 inhibitorpaintinnituscentral nervous system diseasesmental illnessesmood disordersInhibitorinhibitorinhibit

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