HCN2-IN-3
HCN2-IN-3 is an orally active HCN2 inhibitor. HCN2-IN-3 inhibits the activity of HCN2 ion channels. HCN2-IN-3 is applicable to research related to pain, tinnitus, central nervous system diseases, mental illnesses and mood disorders.
For research use only. We do not sell to patients.
- CAS No.: 3080808-83-6
- Formula: C24H21N5O5
- Molecular Weight:459.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
HCN2 modulator-1 (Compound 19) potently and selectively inhibits human HCN2 channels with an IC50 of 9 nM, and exhibits no significant activity against human HCN1 or HCN4 channels[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3080808-83-6
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Molecular Weight 459.45
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Formula C24H21N5O5
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SMILES
N#CC1=C(C2=CN=C3C(C(NC(C4=C(C)OC=C4)=O)=NN3CC(C)OC)=C2)C=CC5=C1OCO5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)